GLPHubglpresearchhub.com
Read-only archive. GLP Research Hub is a static community record — nothing here is for sale, no account is needed, and no vote you cast is counted. Why?
Single comment threadYou are looking at one branch of [Lab] split one vial across PeptideMeter and VendorInvestigate — 98.4% and 97.2% — 53 comments in the full submission. View in context.
2.7k
c/tirzepatide·submitted 1 months ago by u/taper_off_tabitha

[Lab] split one vial across PeptideMeter and VendorInvestigate — 98.4% and 97.2%

Labbranch of 11 comments

Posting this because the title is the whole finding — split one vial across PeptideMeter and VendorInvestigate — 98.4% and 97.2% — and a number without its method is a rumour. 98.4% and 97.2%. Those are measured, not estimated, and not rounded up in my favour. The distribution matters more than the mean. In the trial…

Read the full submission and all 53 comments →

This branch

11 comments, started 1 months ago
u/endpoint_creep26 points·1 months ago

Research-use-only material is not approved for human use. Anything in this thread about how a research vial "should" titrate is a discussion about chemistry, not a plan.

replysharereportpermalink
u/taper_off_tabithaOP10 points·1 months ago

Are you comparing yourself with the trial mean or with the people who post the most?

replysharereportpermalink
u/taper_off_tabithaOP4 points·1 months ago

Week 74 was the first time the scale moved after a five-week stall. I changed nothing in that window.

replysharereportpermalink
u/nabila_ogunleye3 points·1 months ago

week 3 is early to draw any conclusion at all

replysharereportpermalink
u/taper_off_tabithaOP1 point·1 months ago

Came off sema and onto tirz with a two-week gap. The first month was flat and I assumed I had made a mistake. Month two it moved.

replysharereportpermalink
u/forest_plot_fionastats4 points·1 months ago

SURMOUNT-1 ran 72 weeks with the top arm around 21% mean body weight change. SURPASS is the diabetes programme and reports glycaemic endpoints, so quoting the two interchangeably is a category error.

replysharereportpermalink
u/sanne_novak7 points·1 months ago

Yes. I stepped to 12.5 because the calendar said so, not because anything needed fixing, and I regretted it for a fortnight.

replysharereportpermalink
u/sten_palacios2 points·1 months ago

SURMOUNT-1 landed around 21% at 72 weeks on the top arm

replysharereportpermalink
u/kaia_wojcik5 points·1 months ago

The 21% figure is a 72-week mean on the highest arm. Quoting it as what someone should expect by week 86 is not a fair reading.

replysharereportpermalink
load more comments (2) →

← back to the whole thread

About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

187kmembers
130submissions
Aug 2023created
submissions / month, last year
Sponsored

Janoshik Analytical

Independent HPLC and mass spec. The number you get is the number they found.

janoshik.com
Sponsored

GL Biochem (Shanghai)

Custom peptides and amino acids direct from the manufacturer since 1998. ISO 9001 / cGMP. Batch COA every order.

glbiochem.net
c/tirzepatide rules
  1. "Tirz is better than sema" needs a comparator dose or it is a vibe, not a claim.
  2. Vial-splitting and self-compounding discussion stays in c/reconstitution.
  3. No pen-cracking tutorials. Discussing that people do it is fine; instructions are not.
  4. Independent community. Nobody here sells anything, and anyone who tries is banned.
  5. Not medical advice. Describe what you did; never prescribe to a stranger.
  6. Claims need evidence. Batch numbers, dated screenshots, independent test reports, or a citation.
  7. No referral links, discount codes or affiliate URLs. Permanent ban, no appeal.
  8. No contact handles, wallet addresses or tracking numbers — they identify people.
  9. Be recognisably decent. Disagree hard, insult nobody.
Moderators
Volunteers. Unpaid, unaffiliated, and reachable through modmail only.
Before you read on

Several compounds discussed on GLP Research Hub are sold for research use only and are not approved for human use anywhere. Nothing here is medical advice and none of it is written by your clinician. If a post reads like an instruction, treat it as a description of what one stranger did.