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c/tirzepatide·posted 2 years ago by u/hana_pereira

[Question] 15mg — what am I missing here

Question Long Haul ×3 The Quiet One ×1 Receipts ×2

Asking properly rather than in a comment on somebody else’s thread: 15mg — what am I missing here.

Numbers, in the order they matter: 15mg.

Appetite effect for me is flat across seven days. On sema it was a wave. Same person, different molecule.

The thing nobody warned me about was how much of this is logistics — storing it, remembering it, the same day every week.

Happy to answer the boring questions. Those are usually the ones worth asking.

7,743 up / 357 down96% upvoted37 commentsid 14a7e125 Dec 2023

37 comments

9 in this archive, depth 5

best — the order this archive was captured in

u/hair_shed_hannah1.8k points·2 years ago

The distribution matters more than the mean. In the trial population the interquartile spread was wide enough that two honest people can have completely different runs on the same arm.

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u/ahmed_fonseca583 points·2 years ago

sulphur burps are the signature complaint and they are not dangerous

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u/teodor_szabo242 points·2 years ago

That percentage is body weight change, not body fat. Different measurement, and the distinction gets lost every time.

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u/taper_off_tabitha289 points·2 years ago

Correction to my own post above — I said 12.5mg and I have been on 10mg since the spring. Same argument, wrong number.

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u/hassan_nilsen95 points·2 years ago

Correction to my own post above — I said 12.5mg and I have been on 10mg since the spring.

This. The step interval is a floor, and reading it as a timetable is the most expensive mistake in the thread.

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u/hana_pereiraOP122 points·2 years ago

Held 7.5 for five months. Everyone kept asking when I was going to 10. The answer was never, because 7.5 was working.

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u/ignacio_vanhecke848 points·2 years ago

13kg over 32 weeks, never went past 10mg, and nausea stayed mild the whole way. Posting because the loud threads are all 15mg.

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u/hub_opssite staff240 points·2 years ago

Reminder that nobody in this thread is your clinician and the sidebar says so for a reason.

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u/ferritin_low0 points·2 years ago

Push back: "gentler than sema" is a population statement. Plenty of people on this board have the opposite experience and they are not doing it wrong.

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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