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c/t2dglp1·posted 1 year ago by u/neha_falk

[Question] CGM — what am I missing here

Question Long Haul ×1

CGM — what am I missing here. I would rather ask a basic question now than get this wrong quietly for two months.

Kept fingersticks alongside the sensor for two weeks to sanity-check it. Worth doing once.

My ApoB moved and it turned out to have nothing to do with glucose at all.

The order things move in, since nobody explains it and it worries people.

Postprandial excursions generally respond earliest. Variability tends to narrow before the average does, which is visible on a sensor and invisible on a lab result. Fasting glucose is often the laggard, and A1c — being a three-month average — is the last thing to reflect anything.

So a month in which the sensor looks better and the fasting number has not moved is the ordinary sequence, not a contradiction. Knowing that in advance would have saved me a quarter of unnecessary worry, which is why it is worth writing down.

Happy to answer the boring questions. Those are usually the ones worth asking.

490 up / 177 down73% upvoted24 commentsid ylr28a18 May 2025

24 comments

22 in this archive, depth 5

best — the order this archive was captured in

u/sten_palacios67 points·1 year ago

Continuous monitoring shows the shape: postprandial excursions, overnight behaviour and time in range. Two people with identical A1c can have very different distributions.

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u/long_post_larry50 points·1 year ago·edited

Brought the whole CGM export to my appointment rather than one number. Entirely different conversation.

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u/rania_marchand14 points·1 year ago

glycaemic control and weight are two different endpoints

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u/chain_confirm_cpayments24 points·1 year ago

This. Hypoglycaemia risk in this class is driven mostly by the other agents in the regimen.

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u/farid_jansen-15 points·1 year ago

Time in range told me far more than the average did. Two quarters with the same A1c looked completely different on the sensor.

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u/katrin_girard22 points·1 year ago

Postprandial excursions typically respond earlier than fasting glucose, so the sequence people observe is not a sign that something is not working.

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u/neha_falkOP15 points·1 year ago·edited

Small fix — insulin secretion in this class is glucose-dependent, which is precisely why the risk you describe comes from the other agent.

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u/ice_pack_auditcold chain4 points·1 year ago

dose for glycaemic control is not the same conversation as dose for weight

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u/a1c_arcMOD16 points·1 year ago

Identifying details redacted from the exported report above.

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u/step_count_stan13 points·1 year ago

CGM shows you the shape, A1c shows you the area

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u/tomas_lokken5 points·1 year ago

Agreed. A1c is an integrated average over roughly three months and treating it as a current reading causes a lot of unnecessary alarm.

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u/neha_rahimi4 points·1 year ago

What else is in the regimen?

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u/hamza_weiss12 points·1 year ago

Certain conditions affect A1c independently of glycaemia. If a result looks inconsistent with the sensor data, that is a question for whoever manages your care rather than for this board.

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u/neha_falkOP7 points·1 year ago

Is that a first-day sensor reading?

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[deleted]3 points·1 year ago

[deleted]

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u/karim_ramos10 points·1 year ago

a single high reading is not a trend

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u/santiago_rasmussen8 points·1 year ago

check the trial population before quoting a result at somebody

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u/stubborn_batchlist_maybe5 points·1 year ago

Have you taken this to whoever manages your diabetes?

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u/rui_only_ro8 points·1 year ago

A1c reflects average glycaemia over roughly the preceding three months, weighted towards the most recent weeks. It cannot show variability and it lags any change you make.

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u/neha_falkOP6 points·1 year ago

the fasting number is the one people fixate on and it moves last

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u/meal_prep_mira3 points·1 year ago·edited

the fasting number is the one people fixate on and it moves last

Adding the obvious one — bring the export, not the single number, to whoever manages this.

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Type 2 diabetes as the original indication: A1c trajectories, CGM traces, hypoglycaemia risk when stacked with sulfonylureas or insulin, metformin combinations, and why the weight-loss conversation sometimes drowns out the glycaemic one.

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