[Meta] the T2D rule is doing its job and people should stop complaining
the T2D rule is doing its job and people should stop complaining. Nothing about this affects the ranking maths, before anyone asks.
Assumed the weight endpoints from the obesity trials applied to my situation. They are different programmes.
Time in range told me far more than the average did. Two quarters with the same A1c looked completely different on the sensor.
Panicked over a first-day sensor reading and rebuilt my week around it. It was the sensor.
If two or three other people have done the same thing we might actually learn something. Alone it is an anecdote.
best — the order this archive was captured in
Incretin-based agents stimulate insulin secretion in a glucose-dependent manner, which is why hypoglycaemia risk with them alone is low. Risk rises with agents that act independently of glycaemia.
Not convinced. Hypoglycaemia risk from this class alone is low; the risk you are describing comes from the combination.
My ALT moved and it turned out to have nothing to do with glucose at all.
Small fix — insulin secretion in this class is glucose-dependent, which is precisely why the risk you describe comes from the other agent.
Brought the whole CGM export to my appointment rather than one number. Entirely different conversation.
Correction: that trial is the diabetes programme and the figure you quoted is its glycaemic endpoint, not a weight result.
Variability dropped before the average did, which was visible on the sensor and invisible on the lab result.
Cosigning that postprandial excursions improve first and the fasting number is the laggard.
Agreed. A1c is an integrated average over roughly three months and treating it as a current reading causes a lot of unnecessary alarm.
variability matters as much as the mean
Kept fingersticks alongside the sensor for two weeks to sanity-check it. Worth doing once.
the diabetes trials report different endpoints from the obesity ones
nothing here replaces the person managing your diabetes
That is a sensor value, not a plasma value, and the two are not interchangeable at that level of precision.
That A1c change is inside the assay’s variability and the interval you measured over is too short.
- 1Agreed. A1c is an integrated average over roughly three months and treating…6 comments in this branch · started by u/nils_ferreira