[Lab] three BPC vials, three vendors, purity all over the place
Short version of the title, which is already short: three BPC vials, three vendors, purity all over the place. Longer version underneath.
Ask for the theoretical mass alongside the measured one. It is a one-line addition to a certificate and it converts a purity claim into an identity claim.
Research-use-only material is not approved for human use. In this board that is not a formality — it is the reason the clinical evidence base is as thin as it is.
Regulatory classification differs between jurisdictions and has changed in several of them recently. Any answer to a status question needs a place and a date attached.
Happy to answer the boring questions. Those are usually the ones worth asking.
best — the order this archive was captured in
Short peptides in solution are subject to hydrolysis and, depending on sequence, oxidation. Storage state and time in solution are practical variables that this board almost never discusses.
Yes — the rodent literature is real and it is rodent literature. The gap to a human claim is enormous and it gets crossed in one sentence here.
sequence confirmation is the test worth paying for
That is a purity figure, not an identity confirmation. Two different tests and only one answers the question asked.
Reconstituted or powder, and how long has it been in solution?
Cosigning that the papers are more modest than the summaries of them. That is true across this whole site and especially here.
Went and read the primary rodent papers after arguing about a summary for a week. They are much narrower than the threads suggest.
Yes. Nothing here is approved for human use and that should be the first line of every thread, not the last.
Asked GGPeps for the theoretical mass alongside the certificate and they sent it without asking why.
Same. Solution stability is the practical question and almost nobody asks it.
Same.
sequence_checker is right that a pure something-else is still something else.
Disagree — that is a rodent study and you are stating it as a human effect. The distance between those is the entire argument.
a fifteen-residue peptide is easy to make and easy to make badly
Purity by area percent tells you the sample is homogeneous. Mass spectrometry tells you what the homogeneous thing is. For a short peptide, the second question is the one worth paying for.
Is that a clinical claim or a preclinical one?
Do you have the mass spectrum?
short peptides are cheap, which cuts both ways
ask for the mass spectrum, not just the purity number
Was there identity confirmation, or only a purity figure?
pentadecapeptide, fifteen residues, and the sequence is public
pentadecapeptide, fifteen residues, and the sequence is public
This is the point that should be at the top of every thread here. Identity first.
- 1Went and read the primary rodent papers after arguing about a summary for a…7 comments in this branch · started by u/enzo_ferrari
- 2Short peptides in solution are subject to hydrolysis and, depending on…6 comments in this branch · started by u/mariam_cabrera