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c/bloodwork·posted 2 years ago by u/yara_antonsen

baseline labs are the most under-discussed thing on this board

Concerning Long Haul ×8 Slow Clap ×1 Well Actually ×1

baseline labs are the most under-discussed thing on this board. Making the case below, and I expect to lose some of it in the comments.

Time of day, fasting state, hydration and recent exercise all move common markers. Standardising the draw conditions is free and it removes most of the apparent variability.

ApoB counts atherogenic particles rather than the cholesterol they carry, which is why it can diverge from LDL-C and why it is the addition most worth making.

Reference intervals are typically the central 95% of a reference population. By construction one person in twenty falls outside one on any given test without anything being wrong.

Would rather be corrected in public than confident in private.

5,051 up / 448 down92% upvoted22 commentsid 10hhw01 May 2024

22 comments

6 in this archive, depth 2

best — the order this archive was captured in

u/kofi_balogun476 points·2 years ago·edited

Substantial weight loss independently moves lipids, liver enzymes and several other markers. Attributing a change to a compound while losing weight is confounded by design.

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u/a1c_arcT2D376 points·2 years ago

Panicked about a single result, posted here, got told to repeat it, repeated it, and it was fine.

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u/santiago_szabo181 points·2 years ago

That is a non-fasting value and the interval you are comparing it against is a fasting one.

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u/noor_hovland310 points·2 years ago

Careful — that is a question for whoever ordered the panel, and nobody in this thread can answer it responsibly.

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u/karl_fischer_kev248 points·2 years ago

Different laboratories use different assay platforms with different calibration. Comparing across labs adds a systematic offset that is invisible on the report.

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[removed]187 points·2 years ago

[removed by moderator]

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About c/bloodwork

What to measure before you start, what to re-measure, and how to interpret movement without panicking. ApoB over LDL-C, HOMA-IR as a crude free tool, ALT and the fatty-liver story, eGFR noise during rapid loss, and the deficiencies that a 1,100-calorie appetite will hand you.

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