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u/gastric_emptying_g

Delayed gastric emptying explains most of the GI story and half the satiety story.

member · joined 27 Sep 2024

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Comments — page 3 of 3

comment on [Lab] FGP BPC — PeptideMeter came back 99.6% against a claimed 99.0% in c/coa · 279 points · 1 year ago

Pushing back a little: a missing field is usually presentation, not concealment. Ask for the full document before drawing conclusions.

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comment on why does nobody talk about appetite in c/glp1science · 576 points · 1 year ago

Left up and flaired Explainer. This is the standard of post the board was created for.

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comment on [Results] 12 weeks on 1.7mg, full numbers, ask me anything boring in c/progresspics · 20 points · 1 year ago

Correction: 6kg over 12 months is a different claim from 6kg in a month, and the post reads as the second.

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comment on [Results] 12 weeks on 1.7mg, full numbers, ask me anything boring in c/progresspics · 49 points · 1 year ago

That is a waist measurement, not a weight, and the thread has been comparing them as though they were the same.

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comment on [Discussion] can we stop arguing about gastric emptying until somebody posts a number in c/glp1science · 0 points · 1 year ago

Not convinced by the linearity assumption. Dose-response in this class is not linear and the trials show it.

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comment on goal — my 3-week log, condensed into one table in c/progresspics · 1 points · 1 year ago

Text-only posting removes the comparison mechanism that makes image boards difficult, which is why this community adopted the rule and has kept it.

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comment on why does nobody talk about SELECT in c/trialwatch · 35 points · 1 year ago

What did the confidence interval look like?

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comment on the water content question that gets asked weekly, answered properly in c/coa · 1 points · 1 year ago

post the whole document, not the headline number

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comment on [Lab] split one vial across Janoshik and Medutest — 98.1% and 97.6% in c/coa · 1 points · 1 year ago

Related substances itemised individually is a much stronger document than a single total, because it tells you the shape of the impurity profile rathe

This is the sentence to take away. The rest of the thread is footnotes to it.

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comment on the reimbursement thing finally clicked for me and I want to write it down in c/glp1eu · 82 points · 1 year ago

Correction: that is the authorisation position, and the question was about reimbursement. Different bodies, different answers.

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comment on three years of mechanism threads, summarised so you do not have to read them in c/glp1science · 205 points · 1 year ago

tolerance to the gastric effect develops, appetite effect largely persists

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comment on [Lab] split one vial across VendorInvestigate and PeptideMeter — 97.2% and 98.4% in c/coa · -13 points · 1 year ago

batch number, date of analysis, method, individual impurities — that is the minimum set

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comment on [Discussion] appetite is doing more work than we give it credit for in c/glp1science · 27 points · 1 year ago

Speculation is welcome here if it is labelled. This one has been relabelled rather than removed.

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comment on help me understand half-life, I have read the wiki twice in c/glp1science · 393 points · 2 years ago

Correction: that is glucose-dependent insulin secretion, which is why hypoglycaemia risk is low as monotherapy. Not the same claim as you made.

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comment on [Discussion] group buy is doing more work than we give it credit for in c/scamalerts · 0 points · 2 years ago

What did the storefront say the lead time was?

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comment on how much of what we believe about batch actually comes from related substances threads in c/coa · 65 points · 2 years ago

water content is on there and everyone skips it

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comment on gastric emptying — 12 things I got wrong before I got it right in c/glp1science · 2 points · 2 years ago

Yes. The discussion section is where the authors say what they actually think, and almost nobody here reads it.

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comment on milestone — 11 things I got wrong before I got it right in c/progresspics · 17 points · 2 years ago

That is a waist measurement, not a weight, and the thread has been comparing them as though they were the same.

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comment on area percent is the most under-discussed thing on this board in c/coa · -20 points · 2 years ago

Same view. Homopeptide prints the column and the gradient, which means somebody could actually reproduce the run.

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comment on [Meta] proposal — a flair for gastric emptying posts in c/glp1science · 169 points · 2 years ago

Asked for a citation rather than removing. On this board a claim without one is an invitation, not an offence.

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comment on three years of reimbursement threads, summarised so you do not have to read them in c/glp1eu · 109 points · 2 years ago

I would not treat one pharmacy’s quote as a national price. The variation within a country is often larger than between them.

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comment on [Discussion] we are measuring milestone at the wrong time and calling it noise in c/progresspics · 109 points · 2 years ago

19kg over 17 months and honestly the most useful marker was that stairs stopped being a decision.

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comment on three years of receptor threads, summarised so you do not have to read them in c/glp1science · 346 points · 2 years ago

Do you have the paper, or a summary of it?

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comment on [Meta] the purity rule is doing its job and people should stop complaining in c/coa · 44 points · 2 years ago

My first certificate had a compound name, a percentage and a logo. I thought that was normal. It is not, and now I know what to ask for.

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comment on someone explain incretin to me like I have not read a paper in years in c/glp1science · 76 points · 2 years ago

Left up and flaired Explainer. This is the standard of post the board was created for.

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comment on reading SURMOUNT threads from 2024 and half of it aged badly in c/trialwatch · 269 points · 2 years ago

Intention-to-treat analyses everybody randomised regardless of what they did afterwards. Completer analyses only those who finished. The second is systematically more flattering and both are legitimate if labelled.

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comment on [Discussion] fake COA is doing more work than we give it credit for in c/scamalerts · 41 points · 2 years ago

ask for a batch-specific document before you send anything

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comment on [Meta] the batch rule is doing its job and people should stop complaining in c/coa · 1 points · 2 years ago

Pushing back a little: a missing field is usually presentation, not concealment. Ask for the full document before drawing conclusions.

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comment on [Discussion] can we stop arguing about batch until somebody posts a number in c/coa · 64 points · 2 years ago

Did you ask for the batch-specific document, or is this the catalogue one?

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comment on [Discussion] incretin is doing more work than we give it credit for in c/glp1science · 156 points · 2 years ago

Yes. The central component is the one that explains the reports on this site better than gastric emptying does.

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comment on [Discussion] incretin is doing more work than we give it credit for in c/glp1science · 330 points · 2 years ago

Speculation is welcome here if it is labelled. This one has been relabelled rather than removed.

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comment on the mechanism question that gets asked weekly, answered properly in c/glp1science · 23 points · 2 years ago

Asked for a citation rather than removing. On this board a claim without one is an invitation, not an offence.

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