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MACE-3 is not a weight-loss endpoint and that is precisely why SELECT mattered.

member · joined 11 Apr 2025

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Overview — page 2 of 3

comment on three years of dead space threads, summarised so you do not have to read them in c/reconstitution · -28 points · 4 months ago

Correction: that gives 10 units, not what you have written. 30mg into 2mL is 15mg/mL and the division follows from there.

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comment on does prior authorization actually matter or is it forum lore at this point in c/insurancefights · 238 points · 5 months ago

Not convinced. That is a formulary exclusion rather than a prior authorisation denial, and the route to challenge it is different.

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comment on [Discussion] units are doing more work than we give it credit for in c/reconstitution · 178 points · 5 months ago

Disagree with the "more water is safer" framing. It is not safer, it is just a different number to divide by.

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comment on help me understand formulary, I have read the wiki twice in c/insurancefights · 2 points · 5 months ago

Asked for the policy bulletin by number and wrote the appeal against its criteria line by line. Approved on the second level after a flat first-level denial.

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comment on [Discussion] external review is doing more work than we give it credit for in c/insurancefights · 79 points · 6 months ago

The process that has actually worked for people on this board, in order.

Get the denial in writing and find the criterion it names. Request the clinical policy bulletin by its number. Write the appeal against that document, criterion by criterion, attaching what has been tried and for how long. Note the deadline from the letter date and diarise it.

If the first level fails, go to the second. If the second fails, ask about external review, which is independent and, where it applies, binding. Keep every date, department and reference number as you go.

It is administrative rather than rhetorical, and the people who win are the ones who treat it that way.

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comment on my TSH moved and I cannot work out whether ferritin is why in c/bloodwork · 19 points · 6 months ago

My triglycerides moved and I spent a fortnight convinced I knew why. The repeat six weeks later was back in range and I had changed nothing.

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comment on [Discussion] dead space is doing more work than we give it credit for in c/reconstitution · 89 points · 7 months ago

The whole calculation, once, with real numbers.

You have a 20mg vial. You add 2mL of bacteriostatic water. Concentration is mass over volume: 10mg/mL. A U-100 insulin syringe is graduated at 100 units per millilitre, so one unit is 0.01mL.

To draw 0.5mg you need 0.5 divided by 10 millilitres, which is 5 units on the barrel. Write "10mg/mL" on the vial in marker before you put it away, and you never have to do this again for that vial.

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comment on [Meta] the step therapy rule is doing its job and people should stop complaining in c/insurancefights · 57 points · 8 months ago

The process that has actually worked for people on this board, in order.

Get the denial in writing and find the criterion it names. Request the clinical policy bulletin by its number. Write the appeal against that document, criterion by criterion, attaching what has been tried and for how long. Note the deadline from the letter date and diarise it.

If the first level fails, go to the second. If the second fails, ask about external review, which is independent and, where it applies, binding. Keep every date, department and reference number as you go.

It is administrative rather than rhetorical, and the people who win are the ones who treat it that way.

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comment on the external review thing finally clicked for me and I want to write it down in c/insurancefights · 99 points · 8 months ago

Is this a prior authorisation denial or a formulary exclusion?

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comment on the external review thing finally clicked for me and I want to write it down in c/insurancefights · -28 points · 8 months ago

Has a peer-to-peer been offered or requested?

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comment on [Question] how do you actually verify reconstitution in c/reconstitution · 30 points · 8 months ago

Is that a U-100 syringe? The barrel markings change the answer completely.

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comment on [Question] how do you actually verify reconstitution in c/reconstitution · 212 points · 8 months ago

label the vial with the date as well as the concentration

Adding one thing — put the date on the label too. Concentration plus date and you can never mix two vials up.

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comment on reading bacteriostatic water threads from 2024 and half of it aged badly in c/reconstitution · 1 points · 9 months ago

How many mg in the vial and how many mL are you adding?

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comment on how much of what we believe about step therapy actually comes from prior authorization threads in c/insurancefights · 113 points · 10 months ago

Peer-to-peer took fifteen minutes and resolved something a written appeal had been sitting on for a month.

Adding the underused one — external review. Independent, binding where it applies, and hardly anybody gets that far.

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comment on the lost money question that gets asked weekly, answered properly in c/darkspot · 16 points · 1 year ago

Is this the first time, or a pattern you can see now?

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comment on the copay thing finally clicked for me and I want to write it down in c/insurancefights · 19 points · 1 year ago

document what has been tried and for how long, that is the whole case

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comment on the dead space question that gets asked weekly, answered properly in c/reconstitution · 20 points · 1 year ago

The lyophilised cake displaces a small volume, so the true concentration is very slightly lower than the arithmetic suggests.

Right, and the arithmetic behind it: 20mg in 2mL is 10mg/mL, so 2mg is 20 units.

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comment on A1c — 9 things I got wrong before I got it right in c/bloodwork · 14 points · 1 year ago

one measurement is a point, two is a line, three is a trend

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comment on [PSA] units are not what most of this community thinks it is in c/reconstitution · -23 points · 1 year ago

Why "more water" keeps confusing people, including me for a month.

The vial contains a fixed amount of peptide. Water changes nothing about that amount. What it changes is concentration, and concentration is the divisor between the dose you want and the volume you draw.

So doubling the water halves the concentration and doubles the units for the same dose. Nothing is diluted in any sense that matters; you are simply reading a bigger number off the same barrel. Pick the water volume that puts your usual dose on a whole number of units and life gets easier.

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comment on unpopular opinion: most of what gets said here about units are guesswork in c/reconstitution · 91 points · 1 year ago

Started reconstituting everything to a round concentration and the six-in-the-morning error rate went to zero.

rosa_mensah has the units point exactly right. They are a volume on the barrel and nothing else.

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comment on [Discussion] ferritin is doing more work than we give it credit for in c/bloodwork · 60 points · 1 year ago

Tracked A1c against the weight trend for a year. The correlation was much weaker than I expected and that was worth knowing.

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comment on the prior authorization thing finally clicked for me and I want to write it down in c/insurancefights · 2 points · 1 year ago

This. Step therapy is a paperwork requirement and it is beaten with documentation, not persuasion.

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comment on how much of what we believe about concentration actually comes from reconstitution threads in c/reconstitution · 543 points · 1 year ago

reconstituting at a round concentration makes every later dose easy

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comment on does pharmacy actually matter or is it forum lore at this point in c/glp1eu · 119 points · 1 year ago

the reimbursement criteria are published in most member states

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comment on does pharmacy actually matter or is it forum lore at this point in c/glp1eu · 62 points · 1 year ago

The variation between pharmacies inside my own country was larger than the variation I had been chasing across the border.

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comment on does pharmacy actually matter or is it forum lore at this point in c/glp1eu · 114 points · 1 year ago

Apotheke pricing and pharmacy pricing elsewhere are different systems

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comment on [Vendor] GL Biochem vs JEEP on the same compound, same month — both cleared 97.0% in c/darkspot · 51 points · 1 year ago

A public correction of a wrong accusation is worth more to the record than the original report, because it is the thing that keeps the rest of the archive trustworthy.

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comment on how much of what we believe about appeal actually comes from formulary threads in c/insurancefights · 1 points · 1 year ago

employer plans and individual plans are different fights

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comment on how much of what we believe about pharmacy actually comes from EMA threads in c/glp1eu · 3 points · 1 year ago

the language barrier is a real cost and nobody budgets for it

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comment on [Discussion] the appeal advice in here is 2 years out of date in c/insurancefights · 1 points · 1 year ago

Yes — quoting their own policy bulletin back at them is far more effective than arguing in general terms.

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comment on my ApoB moved and I cannot work out whether regret is why in c/darkspot · 1 points · 1 year ago

the regret is usually about pace, not about the decision

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comment on my ApoB moved and I cannot work out whether regret is why in c/darkspot · 1 points · 1 year ago

Correction to my own post: it was my storage, not the shipment. Leaving the original up with this attached.

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comment on my ApoB moved and I cannot work out whether regret is why in c/darkspot · 1 points · 1 year ago

Small correction — the shop in that story has no independent testing on file at all, which is different from having a bad record.

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comment on how much of what we believe about EMA actually comes from pharmacy threads in c/glp1eu · 50 points · 1 year ago

Supply notices are issued nationally. A notice in one member state does not imply availability problems in another, even for the same product.

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comment on [Question] reconstitution — what am I missing here in c/reconstitution · 10 points · 1 year ago

label the vial with the date as well as the concentration

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comment on [Question] how do you actually verify prescription in c/glp1eu · 28 points · 1 year ago

The structure that makes this board make sense, once.

Marketing authorisation for these products is granted centrally, which is why the same product exists across the union. Everything after that — whether it is reimbursed, on what criteria, at what price, in what pack size, dispensed under what margin rules — is decided nationally.

So "is it covered" has twenty-seven answers, "what does it cost" has twenty-seven answers plus within-country variation, and only "is it authorised" has one. Almost every argument on this board is two people answering different questions from different countries, both correctly.

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comment on reading lipids threads from 2024 and half of it aged badly in c/bloodwork · 16 points · 1 year ago

nothing on this board interprets your results for you

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