GLPHubglpresearchhub.com
Read-only archive. GLP Research Hub is a static community record — nothing here is for sale, no account is needed, and no vote you cast is counted. Why?
Single comment threadYou are looking at one branch of does SELECT actually matter or is it forum lore at this point — 51 comments in the full submission. View in context.
5.7k
c/trialwatch·submitted 10 months ago by u/rulebook_rachael

does SELECT actually matter or is it forum lore at this point

Trial Databranch of 7 comments

Asking properly rather than in a comment on somebody else’s thread: does SELECT actually matter or is it forum lore at this point. Compared myself to a trial mean for about six months before realising the trial arm had dietitian contact every fortnight. The discontinuation numbers were the most useful thing in the…

Read the full submission and all 51 comments →

This branch

7 comments, started 10 months ago
u/emil_agyeman434 points·10 months ago

Is that intention-to-treat or completers?

replysharereportpermalink
u/forest_plot_fionaMOD232 points·10 months ago

Left up and flaired Trial Data. The publication is linked rather than the coverage, which is what we ask for.

replysharereportpermalink
u/annika_fonseca88 points·10 months ago

Agreed. Half the arguments on this site are two people quoting different trials at each other without noticing.

replysharereportpermalink
u/naomi_ekstrom314 points·10 months ago

Left up and flaired Trial Data.

Disagreeing with this line: that is a relative reduction and the absolute numbers are considerably less dramatic.

replysharereportpermalink
u/adaeze_weiss217 points·10 months ago

Yes — the interval is the finding. A point estimate with a wide interval is a hypothesis in a nice font.

replysharereportpermalink
u/piotr_bruun215 points·10 months ago

Push back: an open-label extension tells you about the people who stayed. That is a different question.

replysharereportpermalink
u/rina_bergstrom168 points·10 months ago

The press release said that; the publication says something more hedged. Worth reading both.

replysharereportpermalink

← back to the whole thread

About c/trialwatch

Clinical trial reading group. New readouts, protocol amendments, endpoint definitions, dropout handling, and the difference between a press release and a publication. Absolute risk reduction and number-needed-to-treat are house dialect here.

34kmembers
95submissions
Nov 2023created
submissions / month, last year
Sponsored

Sigma-Aldrich Standards

Certified reference materials for peptide identity and purity work.

sigmaaldrich.com
More in c/trialwatch
c/trialwatch rules
  1. Press-release-only posts must be flaired Press Release until a publication exists.
  2. Give the trial name, phase, n, and primary endpoint in the body.
  3. Relative risk reduction alone is not a result. Show the absolute numbers.
  4. Independent community. Nobody here sells anything, and anyone who tries is banned.
  5. Not medical advice. Describe what you did; never prescribe to a stranger.
  6. Claims need evidence. Batch numbers, dated screenshots, independent test reports, or a citation.
  7. No referral links, discount codes or affiliate URLs. Permanent ban, no appeal.
  8. No contact handles, wallet addresses or tracking numbers — they identify people.
  9. Be recognisably decent. Disagree hard, insult nobody.
Full rules and how they are enforced →
Moderators
u/trialwatch_theou/forest_plot_fionau/hazard_ratio_halu/renal_outcomes_r
Volunteers. Unpaid, unaffiliated, and reachable through modmail only.
Before you read on

Several compounds discussed on GLP Research Hub are sold for research use only and are not approved for human use anywhere. Nothing here is medical advice and none of it is written by your clinician. If a post reads like an instruction, treat it as a description of what one stranger did.

Full disclaimer →