[Paper] ATTAIN-1 — an oral pill with no food restrictions is a bigger deal than the % suggests
Something I keep coming back to: ATTAIN-1 — an oral pill with no food restrictions is a bigger deal than the % suggests. Quoted a figure here confidently, got asked whether it was ITT, went and checked, and it was not. Learned something. Started keeping the trial identifiers straight in a note file because I kept…
Open-label extensions lose their randomisation. Anybody still enrolled at week 104 is a selected group and the numbers describe that group.
Agreed. Half the arguments on this site are two people quoting different trials at each other without noticing.
registry entry, protocol, publication — three different documents
Correcting myself upthread: I gave the completer figure and labelled it intention-to-treat.
SURPASS is the diabetes programme and reports glycaemic endpoints
Yes. The appendix tables are where the subgroup and the adverse event detail actually live.
Went looking for the registered protocol to see whether the endpoint had changed. It had not, which was reassuring and worth checking.
the appendix is where the interesting tables live
What did the confidence interval look like?
What did the confidence interval look like?
This is the distinction that would end about half the arguments on this board.