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Single comment threadYou are looking at one branch of [Meta] proposal — a flair for FLOW posts — 33 comments in the full submission. View in context.
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c/trialwatch·submitted 26 days ago by u/paper_trail_paula

[Meta] proposal — a flair for FLOW posts

Press Releasebranch of 6 comments

proposal — a flair for FLOW posts. Nothing about this affects the ranking maths, before anyone asks. The registered protocol is public. Comparing the registered primary endpoint with the reported one is a two-minute check and it is how outcome switching gets caught. Cardiovascular outcome trials are powered for…

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6 comments, started 24 days ago
u/forest_plot_fionaMOD52 points·24 days ago

Left up and flaired Trial Data. The publication is linked rather than the coverage, which is what we ask for.

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u/gastric_emptying_g37 points·24 days ago

A confidence interval is the range of effects compatible with the data. Two trials with overlapping intervals have not disagreed, whatever their point estimates look like next to each other.

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u/britta_boateng17 points·24 days ago

a mean is not a promise

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u/milos_vanhecke53 points·24 days ago

Spent an evening with the appendix tables and found the subgroup detail that the entire thread had been speculating about.

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u/customs_seizure_sid0 points·23 days ago

Agreed on comparators. "Superior" means nothing until you know superior to what and at what dose.

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u/paper_trail_paulaOPvetting16 points·23 days ago·edited

What was the discontinuation rate?

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