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Single comment threadYou are looking at one branch of three years of SURMOUNT threads, summarised so you do not have to read them — 16 comments in the full submission. View in context.
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c/trialwatch·submitted 1 months ago by u/draw_up_dizzy

three years of SURMOUNT threads, summarised so you do not have to read them

Statsbranch of 9 comments

Something I keep coming back to: three years of SURMOUNT threads, summarised so you do not have to read them. Cardiovascular outcome trials are powered for events, not for weight, and are typically run in a different population with different inclusion criteria. Reading a weight number out of one is reading a…

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9 comments, started 28 days ago
u/yusuf_ramos15 points·28 days ago

Spent an evening with the appendix tables and found the subgroup detail that the entire thread had been speculating about.

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u/bastian_ekstrom12 points·28 days ago

The press release said that; the publication says something more hedged. Worth reading both.

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u/first_hundred6 points·28 days ago

a mean is not a promise

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u/marit_laurent8 points·27 days ago

a mean is not a promise

first_hundred is right about the programme names. They are different populations with different endpoints.

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u/joaquin_stanescu4 points·27 days ago

check who the comparator was before you compare anything

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u/draw_up_dizzyOP2 points·27 days ago·edited

discontinuation rate is a result, not a footnote

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[removed]3 points·27 days ago

[removed by moderator]

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u/renal_outcomes_rMOD7 points·28 days ago·edited

Retitled: the original quoted a diabetes endpoint as an obesity result.

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u/anders_kuusela2 points·27 days ago

Retitled: the original quoted a diabetes endpoint as an obesity result.

This is the distinction that would end about half the arguments on this board.

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