reading 15mg threads from 2024 and half of it aged badly
reading 15mg threads from 2024 and half of it aged badly. It is the sort of thing everyone half-believes and nobody writes down. Hard numbers: 15mg. Anything softer than that is flagged as an impression. Came off sema and onto tirz with a two-week gap. The first month was flat and I assumed I had made a mistake.…
Switching from semaglutide, since three people asked in this thread alone.
There is no published dose equivalence between the two. The conversion tables that circulate are somebody’s arithmetic, not data. What people report here is that the first month after a switch is often flat, that the appetite effect feels differently shaped rather than simply stronger, and that starting at the bottom of the ladder again is the common approach.
None of that is a recommendation. It is what the threads say, and the threads are not a clinic.
Yes. I stepped to 12.5 because the calendar said so, not because anything needed fixing, and I regretted it for a fortnight.
Yes.
Agreed, with one qualifier: that is the mean of the top arm and the spread around it was enormous.
Right. And the sema-to-tirz "conversion" people post is invented. There is no published equivalence.
Are you comparing yourself with the trial mean or with the people who post the most?
Careful with "everyone tolerates it better". The people it did not suit stop posting, which makes this board look calmer than the drug is.
2.5mg is a four-week starting dose, not a maintenance dose. Worth being precise since people search these threads.