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c/tirzepatide·submitted 3 months ago by u/zeynep_zielinski

[PSA] VendorInvestigate results are area% by default and people keep forgetting

Labbranch of 8 comments

VendorInvestigate results are area% by default and people keep forgetting. That is the post. The justification is underneath. Week 85 was the first time the scale moved after a five-week stall. I changed nothing in that window. The thing nobody warned me about was how much of this is logistics — storing it,…

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8 comments, started 3 months ago
u/vito_chowdhury58 points·3 months ago

if 7.5 is working, 10 is not automatically better

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u/ingrid_correia44 points·3 months ago

Came off sema and onto tirz with a two-week gap. The first month was flat and I assumed I had made a mistake. Month two it moved.

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u/forest_plot_fionastats10 points·3 months ago

Appetite effect for me is flat across seven days. On sema it was a wave. Same person, different molecule.

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u/titration_marshalmod · c/semaglutide6 points·3 months ago

Appetite effect for me is flat across seven days.

Saving this one. It is the clearest statement of the stall problem I have read here.

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u/ignacio_vanhecke5 points·3 months ago

The 21% figure is a 72-week mean on the highest arm. Quoting it as what someone should expect by week 34 is not a fair reading.

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u/mikkel_kimani10 points·3 months ago

7kg over 22 weeks, never went past 10mg, and injection-site soreness stayed mild the whole way. Posting because the loud threads are all 15mg.

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u/noor_hovland13 points·3 months ago

week 8 is early to draw any conclusion at all

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u/zeynep_zielinskiOP6 points·3 months ago

2.5mg is a four-week starting dose, not a maintenance dose. Worth being precise since people search these threads.

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Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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