2.5 → 5 → 7.5 in six weeks was a mistake, here is what happened
2.5 → 5 → 7.5 in six weeks was a mistake, here is what happened. Change my mind, genuinely — I have no stake in being right about this.
Went 10 to 12.5 on the calendar and had the worst fortnight of the whole run. Dropped back to 10 and everything settled.
Came off sema and onto tirz with a two-week gap. The first month was flat and I assumed I had made a mistake. Month two it moved.
Sulphur burps for the first eight days after each step, then nothing. Predictable enough that I planned my week around it.
Research-use-only material is not approved for human use and nothing here should be read as a recommendation to use it.
best — the order this archive was captured in
The distribution matters more than the mean. In the trial population the interquartile spread was wide enough that two honest people can have completely different runs on the same arm.
the appetite effect is blunter than sema, in a good way, most weeks
Weekly dosing again, half-life in the same neighbourhood as sema, so a step change takes about a month to reach steady state. Judging a new step at day five is judging noise.