TRIUMPH is the most under-discussed thing on this board
TRIUMPH is the most under-discussed thing on this board. Making the case below, and I expect to lose some of it in the comments. Stopped at a low step because there was no reason to go further and no data to tell me what further would do. The thing that surprised me was how much of the discussion here is inference…
Read the phase 2 paper twice before ordering anything. Recommend that to anyone in this board: the error bars are the interesting part.
Correction: TRIUMPH is the phase 3 programme. The number you are quoting is from the phase 2 readout, which is a different trial.
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not approved anywhere, which is the single most important fact in this board
What is the source for that figure — the published paper or a summary of it?
the TRIUMPH programme is still running, so anything definitive is premature
Same read. The energy-expenditure mechanism is the interesting bit and it is not established in humans at scale.
Nothing containing this compound is approved anywhere. Research-use-only material is not approved for human use, and that is a statement of fact rather than a disclaimer.
Increases in heart rate have been reported across this receptor class. The magnitude and clinical significance are exactly what phase 3 is powered to establish.