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c/retatrutide·submitted 1 year ago by u/andres_sorensen

stalled for 12 weeks at 10mg and I refuse to panic this time

Trial Databranch of 9 comments

stalled for 12 weeks at 10mg and I refuse to panic this time. It is the sort of thing everyone half-believes and nobody writes down. 12 weeks and 10mg — those are the numbers, and they are the ones I am willing to defend. The phase 2 readout ran to 48 weeks in a few hundred participants with a slow escalation. Both…

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This branch

9 comments, started 1 year ago
u/incretin_ivyMOD99 points·1 year ago

Removed the escalation schedule. There is no published protocol for members to follow and inventing one here is exactly what this board does not do.

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u/nausea_notesside effects23 points·1 year ago

comparing reta phase 2 to sema phase 3 is comparing different things

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u/reflux_report19 points·1 year ago

wait for phase 3 before you argue about rankings

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u/emil_agyeman8 points·1 year ago·edited

Yes — the comparison threads are apples to oranges and they generate more heat than anything else here.

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u/honest_syringe335 points·1 year ago

nothing here is available as a prescription product, so read every thread with that in mind

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u/anya_moreau61 points·1 year ago

Watched heart rate on a wearable across twelve weeks because the threads said to. It moved a little and I have no idea whether that means anything.

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[deleted]71 points·1 year ago

[deleted]

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u/andres_sorensenOP51 points·1 year ago

Correction: TRIUMPH is the phase 3 programme. The number you are quoting is from the phase 2 readout, which is a different trial.

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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