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c/retatrutide·submitted 2 years ago by u/deleted_my_history

[Results] 26 weeks, 5kg, and dose escalation was the hard part

Resultsbranch of 6 comments

26 weeks, 5kg, and dose escalation was the hard part. Same spreadsheet I have been keeping since the start, nothing retrofitted. Figures up front so nobody has to dig: 26 weeks and 5kg. Glucagon receptor agonism is associated with increased energy expenditure and with hepatic effects. That is a mechanistic story with…

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6 comments, started 2 years ago
u/lane_watchermod · logistics382 points·2 years ago

Flair set to Trial Data since the post is about the published readout rather than an experience.

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u/cormac_roos117 points·2 years ago

Independent purity testing on this compound is thin compared with the older molecules, simply because fewer members have paid for it. Fewer results means wider uncertainty, not a verdict.

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u/deleted_my_historyOP89 points·2 years ago

comparing reta phase 2 to sema phase 3 is comparing different things

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u/burned_once_twice0 points·2 years ago

comparing reta phase 2 to sema phase 3 is comparing different things

Adding the standing caveat: none of this is approved anywhere and research material is not for human use.

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u/trialwatch_theotrial nerd61 points·2 years ago

heart rate is the thing people report watching

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u/halima_mbeki261 points·2 years ago

the escalation is where most of the reported trouble sits

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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