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c/retatrutide·submitted 1 year ago by u/freya_baptista

[Lab] WXT reta — PeptideMeter came back 97.7% against a claimed 97.0%

Labbranch of 6 comments

Short version of the title, which is already short: WXT reta — PeptideMeter came back 97.7% against a claimed 97.0%. Longer version underneath. Pulling the figures out of the title: 97.7% and 97.0%. All of it is written down as it happened rather than reconstructed. Read the phase 2 paper twice before ordering…

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6 comments, started 1 year ago
u/isabela_nilsen264 points·1 year ago

What do you think the glucagon component is adding, specifically?

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u/tired_ledger_notes-14 points·1 year ago

Push back: quoting the phase 2 headline as an expected outcome is not a fair reading of a small trial with wide intervals.

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u/cold_chromatogram_only1 point·1 year ago

the phase 2 numbers were striking and they were also 48 weeks in a small population

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u/freya_baptistaOP1 point·1 year ago

That is body weight change, not fat mass. The trials report the first and people quote it as the second.

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u/incretin_ivyMOD164 points·1 year ago

Left up. It reads the phase 2 paper carefully and it is honest about the intervals.

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u/cold_chromatogram_only121 points·1 year ago

What do you think the glucagon component is adding, specifically?

This is the sentence the rest of the board should read first. Phase 2 is not a label.

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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