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c/retatrutide·posted 2 years ago by u/iman_castellanos

small win: triple agonist stopped being a problem at week 65

Discussion Receipts ×4 Well Actually ×2 Cold Box ×3

small win: triple agonist stopped being a problem at week 65, and the part I actually want to talk about is at the bottom.

The early fullness profile felt different rather than worse. Hard to describe and impossible to quantify, so take it as an impression.

Watched heart rate on a wearable across twelve weeks because the threads said to. It moved a little and I have no idea whether that means anything.

Not medical advice, obviously, and nothing here is approved for human use. One person with a spreadsheet.

8,283 up / 291 down97% upvoted12 commentsid 1art9n20 Dec 2023

12 comments

8 in this archive, depth 3

best — the order this archive was captured in

u/nabila_bakken1.6k points·2 years ago

It is a triple agonist at the GLP-1, GIP and glucagon receptors. The glucagon arm is the genuinely novel component and it is the one with the least human outcome data behind it.

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u/iman_castellanosOP1.1k points·2 years ago·edited

It is a triple agonist at the GLP-1, GIP and glucagon receptors.

Adding the standing caveat: none of this is approved anywhere and research material is not for human use.

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u/arne_amankwah1.1k points·2 years ago

Nothing containing this compound is approved anywhere. Research-use-only material is not approved for human use, and that is a statement of fact rather than a disclaimer.

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u/noor_ivaturi258 points·2 years ago

a lot of the confident posting here is extrapolation

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u/iman_castellanosOP-2 points·2 years ago

a lot of the confident posting here is extrapolation

Disagree with this specific inference. A 48-week readout does not tell you the shape of the curve after it.

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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