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c/reconstitution·submitted 2 years ago by u/saskia_mwangi

[Discussion] mg/mL is doing more work than we give it credit for

Discussionbranch of 6 comments

Something I keep coming back to: mg/mL is doing more work than we give it credit for. Bacteriostatic water contains benzyl alcohol as a preservative, which is what makes repeated entry into the same vial reasonable. Plain sterile water has no preservative. If your calculation produces a fraction of a unit, the…

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6 comments, started 2 years ago
u/swirl_dont_shakereconstitution26 points·2 years ago

Research-use-only material is not approved for human use, so treat everything in this thread as arithmetic about solutions rather than instructions for a person.

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u/saskia_mwangiOP11 points·2 years ago

Did the maths give you a whole number of units, or a fraction?

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u/zaid_balogun3 points·2 years ago

dead space in the needle hub is real and it is small

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u/nadia_kjaer2 points·2 years ago

Show the arithmetic — where did the unit figure come from?

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u/saskia_mwangiOP1 point·2 years ago

Started reconstituting everything to a round concentration and the six-in-the-morning error rate went to zero.

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u/saskia_mwangiOP18 points·2 years ago

units are a volume on a U-100 syringe, not a dose

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About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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