GLPHubglpresearchhub.com
Read-only archive. GLP Research Hub is a static community record — nothing here is for sale, no account is needed, and no vote you cast is counted. Why?
Single comment threadYou are looking at one branch of why does nobody talk about units — 65 comments in the full submission. View in context.
806
c/reconstitution·submitted 2 years ago by u/liv_nkemelu

why does nobody talk about units

Questionbranch of 7 comments

The title is the whole question — why does nobody talk about units — but here is why I am asking. Started reconstituting everything to a round concentration and the six-in-the-morning error rate went to zero. The dead space question sent me down a rabbit hole for a week. It is a fraction of a unit and it is the same…

Read the full submission and all 65 comments →

This branch

7 comments, started 2 years ago
u/cardio_endpoint_c152 points·2 years ago

Why "more water" keeps confusing people, including me for a month.

The vial contains a fixed amount of peptide. Water changes nothing about that amount. What it changes is concentration, and concentration is the divisor between the dose you want and the volume you draw.

So doubling the water halves the concentration and doubles the units for the same dose. Nothing is diluted in any sense that matters; you are simply reading a bigger number off the same barrel. Pick the water volume that puts your usual dose on a whole number of units and life gets easier.

replysharereportpermalink
u/viktor_erdogan52 points·2 years ago

Same. I got this wrong once, caught it because the units looked absurd, and have written on every vial since.

replysharereportpermalink
u/RetaAndRegret240 points·2 years ago

Yes. Writing 10mg/mL on the vial takes four seconds and removes the entire class of error this board exists to fix.

replysharereportpermalink
u/niels_roos13 points·2 years ago

I would not round that figure. At 10mg/mL a rounding error of two units is a real fraction of the intended amount.

replysharereportpermalink
[removed]58 points·2 years ago

[removed by moderator]

replysharereportpermalink
u/karim_ilunga36 points·2 years ago

a U-100 syringe reads 100 units to the millilitre, every time

replysharereportpermalink
u/alcohol_aversion116 points·2 years ago

Correction: that gives 40 units, not what you have written. 5mg into 2mL is 2.5mg/mL and the division follows from there.

replysharereportpermalink

← back to the whole thread

About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

88kmembers
130submissions
Aug 2023created
submissions / month, last year
Sponsored

Sigma-Aldrich Standards

Certified reference materials for peptide identity and purity work.

sigmaaldrich.com
c/reconstitution rules
  1. Show your numbers. "How many units?" with no mg and no mL cannot be answered.
  2. Never post a calculation as advice without stating the concentration it assumes.
  3. No sterile-compounding-for-others discussion. Personal handling only.
  4. Independent community. Nobody here sells anything, and anyone who tries is banned.
  5. Not medical advice. Describe what you did; never prescribe to a stranger.
  6. Claims need evidence. Batch numbers, dated screenshots, independent test reports, or a citation.
  7. No referral links, discount codes or affiliate URLs. Permanent ban, no appeal.
  8. No contact handles, wallet addresses or tracking numbers — they identify people.
  9. Be recognisably decent. Disagree hard, insult nobody.
Moderators
Volunteers. Unpaid, unaffiliated, and reachable through modmail only.
Before you read on

Several compounds discussed on GLP Research Hub are sold for research use only and are not approved for human use anywhere. Nothing here is medical advice and none of it is written by your clinician. If a post reads like an instruction, treat it as a description of what one stranger did.