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c/reconstitution·submitted 1 year ago by u/runa_grimaldi

someone explain mg/mL to me like I have not read a paper in years

PSAbranch of 7 comments

someone explain mg/mL to me like I have not read a paper in years. I am not trying to be the "source?" guy. I would just like a source. The lyophilised cake displaces a small volume, so the true concentration is very slightly lower than the arithmetic suggests. It is a fraction of a percent and it is dwarfed by fill…

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7 comments, started 1 year ago
u/ines_lindqvist116 points·1 year ago

bacteriostatic water has the preservative, sterile water does not

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u/alcohol_aversion49 points·1 year ago

This. Showing the working is the fastest way for somebody else to spot the mistake.

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u/honest_syringe_maybe29 points·1 year ago

This.

Adding one thing — put the date on the label too. Concentration plus date and you can never mix two vials up.

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u/RetaAndRegret29 points·1 year ago

do the arithmetic before you reconstitute, not while holding a syringe

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u/kavya_radich4 points·1 year ago

Agreed on the swirl. There is no reason to shake it and a good reason not to.

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[deleted]18 points·1 year ago

[deleted]

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u/hedda_adeyemi14 points·1 year ago

label the vial with the date as well as the concentration

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About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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