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c/glp1muscle·posted 4 months ago by u/bilal_adebayo

help me understand sarcopenia, I have read the wiki twice

Question Receipts ×8 Slow Clap ×3

The title is the whole question — help me understand sarcopenia, I have read the wiki twice — but here is why I am asking.

Some lean mass loss accompanies weight loss in any deficit. Resistance training and adequate protein intake are the two interventions with the best evidence for limiting the proportion.

On comparing yourself to composition figures from trials.

Published composition data comes from supervised populations with structured protocols, standardised scanning, and analysis populations that have been defined in advance. Your two scans at a local clinic, taken in different states of hydration, are not the same measurement.

Use your own baseline. The question worth asking is whether your own trajectory is going the way you want given what you are actually doing, and the honest answer usually requires measuring protein rather than estimating it and being truthful about training frequency. Neither of those is advice — a programme and a target are things to work out with somebody who knows your history.

How to make a DEXA comparison mean anything.

Same machine, same clinic, same protocol. Same hydration and fasting state, as far as you can manage. At least three to four months apart, because the measurement error is large relative to short-term change. Three scans rather than two, because the first pair cannot distinguish a trend from noise.

Do less than that and you have two numbers with an offset of unknown size, which people then react to by rebuilding a training programme. The free alternative — a few tracked lifts and a monthly waist measurement — is directionally informative, costs nothing, and is far harder to over-interpret.

Corrections welcome, especially the pedantic ones. Pedantry is how this board earns its reputation.

1,182 up / 34 down97% upvoted47 commentsid oxvlb25 Mar 2026

47 comments

19 in this archive, depth 5

best — the order this archive was captured in

u/rasmus_kuipers108 points·4 months ago

DEXA has a meaningful coefficient of variation, and it differs between machines and protocols. Comparing scans from different clinics adds a systematic offset that is invisible on the report.

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u/aksel_kjaer129 points·4 months ago

Agreed on the error margin. Quoting a DEXA to one decimal implies a precision the method does not have.

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u/throwaway_wl2026106 points·4 months ago

Kept the same programme for a year instead of changing it every six weeks. That was the change that worked.

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u/greta_perrin62 points·4 months ago

do not compare your composition to a trial average

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u/tomas_lundgren62 points·4 months ago

Same. Volume over novelty. Changing programme every six weeks cost me a year.

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u/trialwatch_theotrial nerd39 points·4 months ago

Two scans on the same machine 15 months apart. Lean mass held better than I expected and the lifts told the same story for free.

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[deleted]16 points·4 months ago

[deleted]

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u/bilal_adebayoOP6 points·4 months ago·edited

Correcting myself upthread: 22 months between scans, not the figure I gave.

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u/bilal_adebayoOP0 points·4 months ago

How many weeks between the two scans?

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u/draw_up_dizzy1 point·4 months ago

Have the lifts held, dropped, or moved around?

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u/greta_lokken57 points·4 months ago

Tracked grip strength and three lifts monthly. Cheaper than scanning and directionally the same answer.

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u/ahmed_fonseca24 points·4 months ago·edited

Protein was the whole problem. Appetite dropped and I was eating well under target without noticing for a month.

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u/bilal_adebayo20 points·4 months ago

I would not change the programme on the strength of one scan. The measurement error is larger than the effect you are reacting to.

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u/annika_fonseca-2 points·4 months ago

lean mass loss during weight loss is expected, the question is how much

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u/plain_titration1 point·4 months ago

Started weighing protein rather than estimating it. The gap between what I thought and what I ate was embarrassing.

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u/constipation_clubside effects1 point·4 months ago

resistance training first, cardio if there is time left

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u/lift_heavy_thingsMOD40 points·4 months ago

Removed a prescriptive nutrition target aimed at another member. Describe your own intake instead.

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u/bilal_adebayoOP30 points·4 months ago

Removed a prescriptive nutrition target aimed at another member.

lift_heavy_things is right that protein becomes a logistics problem when appetite drops.

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Lean-mass retention during rapid weight loss: protein targets, resistance-training minimums, DEXA and BIA measurement reality, FFMI tracking, and the sarcopenia question that nobody funded a proper trial for.

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