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c/glp1muscle·posted 1 year ago by u/reflux_report

tried protein for 24 weeks. here is what happened.

Data Clean Column ×5

Something I keep coming back to: tried protein for 24 weeks. here is what happened.

Pulling the figures out of the title: 24 weeks. All of it is written down as it happened rather than reconstructed.

Reduced appetite makes hitting a protein target a logistics problem rather than a motivation problem, which is why the practical advice here is about timing and food choice rather than willpower.

Strength retention is an imperfect but free longitudinal proxy: it is affected by neural factors and by being in a deficit, so it tracks tissue change loosely rather than exactly.

Not medical advice, obviously, and nothing here is approved for human use. One person with a spreadsheet.

764 up / 163 down82% upvoted26 commentsid 40zewx4 Apr 2025

26 comments

23 in this archive, depth 3

best — the order this archive was captured in

u/lift_heavy_thingsMOD136 points·1 year ago

Left up. Same machine, stated conditions, honest about the error margin.

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u/skip_week_sceptic92 points·1 year ago

Same DEXA machine both times?

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u/matias_falk-11 points·1 year ago

Two scans on the same machine 10 months apart. Lean mass held better than I expected and the lifts told the same story for free.

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u/adaeze_cabrera1 point·1 year ago

Disagree — slower loss does not automatically preserve lean mass. Protein and training do the work, not the rate on its own.

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u/edit_for_clarity-16 points·1 year ago

Some lean mass loss accompanies weight loss in any deficit. Resistance training and adequate protein intake are the two interventions with the best evidence for limiting the proportion.

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u/adaeze_cabrera86 points·1 year ago·edited

Hydration status and fasting state affect the lean mass estimate. Standardising both is the difference between a comparison and a coin toss.

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u/liv_dumitru59 points·1 year ago

What was the rate of weight change over that window?

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[deleted]22 points·1 year ago

[deleted]

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u/prior_auth_painappeals51 points·1 year ago

Three scans over eighteen months, same machine, same conditions. Only the third one made the first two interpretable.

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u/joaquin_trevino36 points·1 year ago

Cosigning that protein gets harder precisely when appetite drops. That is the actual difficulty and it is logistical.

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u/viktor_girard20 points·1 year ago

DEXA has a meaningful coefficient of variation, and it differs between machines and protocols. Comparing scans from different clinics adds a systematic offset that is invisible on the report.

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u/emil_okwuosa29 points·1 year ago

Fat-free mass index is a ratio of fat-free mass to height squared. It moves when either term does, which makes it awkward to interpret during active weight change.

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u/janek_ferrari20 points·1 year ago·edited

Small fix — that is fat-free mass, not muscle mass. The scan cannot separate them the way the post assumes.

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u/reflux_reportOP11 points·1 year ago

Lost slower for six months deliberately and my composition change was not obviously different. Training was what mattered.

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u/arne_amankwah14 points·1 year ago

Compared two scans from different clinics and panicked over a difference that was inside the error margin.

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u/erez_yilmaz10 points·1 year ago

Push back: strength dropping in a deficit is not the same as lean mass loss. Related, not identical.

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u/reflux_report15 points·1 year ago

What the evidence actually supports, stripped of the arguing.

Some lean mass is lost in any weight-loss deficit. Resistance training and adequate protein intake are the two interventions with real support for limiting the proportion. Nearly everything else discussed on this board is a rounding error on those two.

The complication specific to this site is that appetite reduction makes protein intake a logistics problem: you are being asked to eat a fixed amount of something at exactly the point when eating anything is less appealing. That is why the practical threads here are about timing and food choice rather than motivation, and why measuring intake rather than estimating it is the single most common useful correction.

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u/sarcopenia_watch7 points·1 year ago·edited

What the evidence actually supports, stripped of the arguing.

Agreed — and same machine, same conditions, or the two scans are not comparable.

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u/constipation_clubside effects2 points·1 year ago

grip strength and lift numbers are cheap longitudinal markers

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u/yannick_haddad9 points·1 year ago·edited

resistance training first, cardio if there is time left

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Lean-mass retention during rapid weight loss: protein targets, resistance-training minimums, DEXA and BIA measurement reality, FFMI tracking, and the sarcopenia question that nobody funded a proper trial for.

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