c/coa · created 18 Aug 2023
Certificates of analysis, decoded. Post the whole document, not the headline number.
I have typed some version of this comment about four hundred times so it is going in one place. Area% is the main peak as a fraction of total UV absorbance across all…
Following on from the area% thread, because the same confusion turns up in a second form. People read a 10mg vial at 99% purity and conclude they have 9.9mg of peptide.…
Trying to work out what makes a document a result rather than a general statement about a product line. The one in front of me — FGP cagrilintide — has a compound name,…
Short answer, for anyone who finds this from a search: no. Longer version. A COA from an actual laboratory is exported from instrument software or from a LIMS. The PDF…
Reference standards, analytical reagents and system-suitability material. If you are running your own method, start with a known.
Reference standardsRan these on the same day, same method, same column, injections back to back. One is GL Biochem raw material, one is a reseller vial of nominally the same compound and…
CPC semaglutide 10mg. COA says 96.8%, method line says "HPLC", batch and date both present. Nothing cropped, whole page. Everyone in here talks about 98 and 99 like…
Title says it — is 96.8% area% actually fine or am i being sold a rounding error — so here is the boring supporting detail that makes it worth anything. 96.8%. Those…
How to read a certificate of analysis and what it does and does not tell you. Area% versus mass%, identity versus quantity, water content, related substances, acetate counterions, and the difference between a vendor-supplied COA and an independent test on the vial you actually received.
Certified reference materials for peptide identity and purity work.
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