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c/coa·posted 6 days ago by u/alcohol_aversion

is 96.8% area% actually fine or am i being sold a rounding error

Question

Title says it — is 96.8% area% actually fine or am i being sold a rounding error — so here is the boring supporting detail that makes it worth anything.

96.8%. Those are measured, not estimated, and not rounded up in my favour.

LC-MS gives you identity; UV purity gives you a relative quantity. A document with the first and not the second, or the reverse, is answering half the question.

Ask what the stability statement was written against — temperature, light, and whether it was the lyophilised powder or the reconstituted solution. Those are three different claims.

Research-use-only material is not approved for human use and nothing here should be read as a recommendation to use it.

0 up / 0 down47% upvoted4 commentsid taaage24 Jul 2026

4 comments

4 in this archive, depth 2

best — the order this archive was captured in

u/first_hundred0 points·5 days ago

Area percent is the peak area of your compound over the total integrated area, at one wavelength, on one gradient. It is a relative measure of what the detector saw, not a mass fraction of the vial.

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u/purity_pedantMOD1 point·5 days ago

Reminder: a question about a document is not an accusation about a supplier, and posts that blur the two get retitled.

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u/tuva_aalto4 points·5 days ago

That is not what the method line says. It names the technique; it does not certify the operator.

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About c/coa

How to read a certificate of analysis and what it does and does not tell you. Area% versus mass%, identity versus quantity, water content, related substances, acetate counterions, and the difference between a vendor-supplied COA and an independent test on the vial you actually received.

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