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c/bpc157·submitted 1 year ago by u/karim_hartmann

tendon: what the trials say vs what this community says

Questionbranch of 13 comments

tendon: what the trials say vs what this community says — a position I have arrived at slowly and would like tested. The evidence base, described honestly, which almost no summary of it does. The published literature is overwhelmingly preclinical and largely in rodent models. The individual papers are generally more…

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13 comments, started 1 year ago
u/neha_rahimi56 points·1 year ago

Paid for identity confirmation rather than just purity for the first time here. Worth it, and it is not the default on most certificates.

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u/sofia_ferreira39 points·1 year ago

That claim traces back to a single preclinical paper that says something considerably narrower.

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u/isabela_nilsen11 points·1 year ago

Small fix — fifteen residues, not seventeen. The sequence is public and easy to check.

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u/karim_hartmannOP8 points·1 year ago

Do you have the mass spectrum?

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u/honest_syringe3 points·1 year ago

no clinical trial has established what these threads assert

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u/taper_off_tabitha31 points·1 year ago

pentadecapeptide, fifteen residues, and the sequence is public

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u/rekha_mwangi9 points·1 year ago

Same. Solution stability is the practical question and almost nobody asks it.

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u/vikram_mbeki13 points·1 year ago·edited

Right, and regulatory status has genuinely moved in several jurisdictions. Answers from three years ago may be wrong now.

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u/honest_syringe-13 points·1 year ago

the human evidence is thin and the rodent evidence is not

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u/baseline_drifteranalytical9 points·1 year ago

Went and read the primary rodent papers after arguing about a summary for a week. They are much narrower than the threads suggest.

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u/kaplan_meier_kim7 points·1 year ago

Bought small, tested identity first, and only then thought about anything else. That order felt right.

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u/enzo_fonseca10 points·1 year ago

regulatory status varies by jurisdiction and it has moved recently

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u/ilias_steiner5 points·1 year ago

identity, quantity, stability — three separate questions

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BPC-157 as it actually is: a pentadecapeptide with a genuinely interesting rodent tendon-and-gut literature, near-zero controlled human data, a naming and sequence mess in the supply chain, and a regulatory status that changed sharply in several countries.

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