rodent data — 9 things I got wrong before I got it right
The title is the argument: rodent data — 9 things I got wrong before I got it right. Here is the rest of it. Ask for the theoretical mass alongside the measured one. It is a one-line addition to a certificate and it converts a purity claim into an identity claim. Research-use-only material is not approved for human…
The published literature is overwhelmingly preclinical, largely in rodent models. Translating a rodent result into a human expectation is not a small step, and almost every confident claim here takes it silently.
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Every claim I could trace in this board went back to about four papers. That was a sobering afternoon.
Yes — the rodent literature is real and it is rodent literature. The gap to a human claim is enormous and it gets crossed in one sentence here.
Is that a clinical claim or a preclinical one?
the human evidence is thin and the rodent evidence is not