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c/bloodwork·posted 1 year ago by u/kenji_kimani

what would you tell week-1 you about ALT

Concerning Cold Box ×4

Genuine question, and the title is the question: what would you tell week-1 you about ALT.

Panicked about a single result, posted here, got told to repeat it, repeated it, and it was fine.

Tracked triglycerides against the weight trend for a year. The correlation was much weaker than I expected and that was worth knowing.

Draw at the same point in the week now, fasting, same lab. The noise dropped enormously once I standardised.

That is everything I have. The rest is opinion and I have tried to keep it out.

713 up / 188 down79% upvoted19 commentsid 2lwmsf20 Apr 2025

19 comments

10 in this archive, depth 5

best — the order this archive was captured in

u/mikkel_kimani90 points·1 year ago

Time of day, fasting state, hydration and recent exercise all move common markers. Standardising the draw conditions is free and it removes most of the apparent variability.

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u/iman_falk22 points·1 year ago·edited

Is that the same assay, or did the lab change platforms?

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u/coring_the_stopper62 points·1 year ago

Small fix — a reference interval is not a treatment target, and the post above uses them interchangeably.

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u/nabila_bakken41 points·1 year ago

Correction: that marker is reported in different units by different labs, which explains the tenfold difference you are seeing.

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u/anders_vermeulen20 points·1 year ago

same lab, same conditions, or you are comparing noise

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u/nnt_nate16 points·1 year ago

That comparison crosses two labs with different assays. The difference you are describing may be the method.

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u/kaia_kuusela46 points·1 year ago

How many weeks between the two measurements?

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u/liver_enzyme_liz11 points·1 year ago·edited

Have you taken this to whoever ordered it?

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u/vito_chowdhury0 points·1 year ago

Have you taken this to whoever ordered it?

This is the sentence to read before anybody panics about a single value.

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u/flair_enthusiast16 points·1 year ago·edited

Disagree with reading anything into that. One value, one morning, and you changed two other things in the same window.

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About c/bloodwork

What to measure before you start, what to re-measure, and how to interpret movement without panicking. ApoB over LDL-C, HOMA-IR as a crude free tool, ALT and the fatty-liver story, eGFR noise during rapid loss, and the deficiencies that a 1,100-calorie appetite will hand you.

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