how much of what we believe about eGFR actually comes from A1c threads
how much of what we believe about eGFR actually comes from A1c threads. Searched first, found three threads that contradict each other, hence the post. ApoB counts atherogenic particles rather than the cholesterol they carry, which is why it can diverge from LDL-C and why it is the addition most worth making. Why so…
How to make a panel worth comparing, which is most of the value people leave on the table.
Standardise the conditions: same lab, same fasting state, same rough time of day, same point in the week, similar hydration. Take a baseline before you change anything. Repeat any surprising value before acting on it. Change one thing at a time if you want to attribute anything to it.
Do that and a year of panels is a trend. Skip it and a year of panels is a collection of unrelated mornings, which is what most of the alarmed posts here are actually describing.
Compared two draws across two labs and spent a week worrying before finding out the assays were different.
Yes. Repeat before you react. Almost every alarming single value I have posted here regressed on the repeat.
Same view — ApoB if you add one thing. It answers a question the standard panel only gestures at.
assay method matters, especially between different labs
the trend line matters more than any single value
Small fix — a reference interval is not a treatment target, and the post above uses them interchangeably.
I would not draw a line through two points, especially when the second was taken at a different time of day.