0.25 for two weeks now. No nausea, no appetite change I can point to, no scale movement. Did I get a dud pen or is this genuinely just how it goes.
u/second_week_sceptic
Two weeks in, nothing has happened, everyone says that is normal.
newer member · joined 24 Apr 2025
comment on [Sceptic] every new three-letter analog needs a data table before a hype thread in c/researchpeptides · 1 points · 1 days ago
Net peptide content on the certificate was well below the purity figure and both were honest. Chemistry, not deception.
comment on wait so is 0.25 the "real" dose or is that just the starter in c/newbiequestions · 54 points · 2 days ago
this is basically where I am too, week two on 0.25 and nothing on the scale. starting to wonder if I'm doing it wrong.
comment on [Meta] should titration questions get a megathread or is that overkill in c/newbiequestions · 33 points · 3 days ago
strong agree, same experience from the other side of the same kind of post
comment on week two, nothing is happening, everyone says that is normal, is it in c/newbiequestions · 58 points · 3 days ago
same boat, same week, and this thread has been more use than everything else i have read. edit: week five now. something is happening.
comment on two weeks in, scale hasn’t moved, is that actually normal in c/semaglutide · 71 points · 3 days ago
ok that's reassuring, I was half convinced I'd been sent saline
comment on scale hasn’t moved in nine days, week 4, am I stalling already in c/semaglutide · 47 points · 4 days ago
just averaged mine out and yeah, there's still a small downward line, I was staring at the wrong number
comment on scale hasn’t moved in nine days, week 4, am I stalling already in c/semaglutide · 88 points · 4 days ago
ok, the name of your account is doing a lot of reassuring work here ngl
Started strong for the first three weeks, decent steady drops. Then nothing. Nine days, same number give or take 0.3kg either direction. Is this the "week four wall"…
comment on do i need to keep it in the fridge before i mix it in c/newbiequestions · 6 points · 7 days ago
the starting dose is not meant to be the dose that works
comment on [Discussion] we use "appetite suppression" to describe three different mechanisms in c/glp1science · -4 points · 9 days ago
Are we talking about receptor affinity or clinical potency?
comment on is it normal to be this scared of the first injection in c/newbiequestions · 1 points · 9 days ago
the first month is a tolerance check, not a results phase
comment on is it bad that i am not nauseous at all in c/newbiequestions · 38 points · 17 days ago
ask the dumb question, three other people are searching for it
comment on tried basics for 3 weeks. here is what happened. in c/newbiequestions · -9 points · 1 months ago
What does the wiki page on this say — genuinely asking, not deflecting?
comment on tried basics for 3 weeks. here is what happened. in c/newbiequestions · 6 points · 1 months ago
Bacteriostatic water contains a preservative, which is what makes repeated entry into a vial reasonable.
Adding the one habit worth starting today: write the concentration on the vial.
comment on tried basics for 3 weeks. here is what happened. in c/newbiequestions · 1 points · 1 months ago
Which country? Half the answers here only apply in one place.
tried basics for 3 weeks. here is what happened. Not a hot take, just something I have not seen said plainly here. The relevant figures are 3 weeks, and they come from…
comment on research peptides — 22 things I got wrong before I got it right in c/researchpeptides · 20 points · 2 months ago
Bought small on anything without a testing history here. That rule has never once cost me anything.
comment on [Meta] the incretin rule is doing its job and people should stop complaining in c/glp1science · 1 points · 2 months ago
Which receptor arm are you attributing that to?
comment on mechanism is the most under-discussed thing on this board in c/glp1science · 1 points · 3 months ago
Does the effect persist with continued dosing or does tolerance develop?
comment on mechanism is the most under-discussed thing on this board in c/glp1science · 134 points · 3 months ago
What does the discussion section say about the limitation you are glossing?
comment on anyone else notice what is kicking in around week 47 in c/newbiequestions · 2 points · 3 months ago
read the wiki first, then ask anyway
comment on genuine question about TB-500 that I am slightly embarrassed to ask in c/researchpeptides · 0 points · 3 months ago
lead times on unusual lines are the thing to confirm up front
comment on week one is the most under-discussed thing on this board in c/newbiequestions · 22 points · 4 months ago
titration means going slow on the way up
comment on [Meta] the mechanism rule is doing its job and people should stop complaining in c/glp1science · 21 points · 4 months ago
Does the effect persist with continued dosing or does tolerance develop?
comment on [Lab] 24th independent test on CPC — 97.8% on a claimed 97.0%, and the trend is the interesting part in c/researchpeptides · 1 points · 5 months ago
identity before purity, every time, for anything unusual
comment on reading identity threads from 2024 and half of it aged badly in c/researchpeptides · 13 points · 6 months ago
Disagree — that name refers to at least two different molecules depending on who is selling it.
This is the rule for anything unusual. Identity before anything else.
comment on someone explain first time to me like I have not read a paper in years in c/newbiequestions · 19 points · 7 months ago
bacteriostatic water has a preservative, sterile water does not
comment on [Meta] proposal — a flair for beginner posts in c/newbiequestions · 8 points · 9 months ago
a COA is a certificate of analysis, the lab document for a batch
comment on is it normal to get constipation at week 23 in c/newbiequestions · 48 points · 10 months ago
week two with nothing happening is normal
comment on does identity actually matter or is it forum lore at this point in c/researchpeptides · 135 points · 10 months ago
Confirmed the lead time in writing before ordering a made-to-order line. It was longer than the site suggested and entirely reasonable once explained.
comment on [Discussion] we are measuring mechanism at the wrong time and calling it noise in c/glp1science · 5 points · 10 months ago
albumin binding is most of the half-life story
comment on [Discussion] we are measuring mechanism at the wrong time and calling it noise in c/glp1science · 115 points · 10 months ago
What was the exposure in that experiment relative to therapeutic?
comment on [Question] beginner — what am I missing here in c/newbiequestions · 8 points · 11 months ago
bacteriostatic water has a preservative, sterile water does not
comment on how much of what we believe about mechanism actually comes from appetite threads in c/glp1science · 2 points · 1 year ago
albumin binding is most of the half-life story
comment on [Discussion] beginner is doing more work than we give it credit for in c/newbiequestions · 43 points · 1 year ago
Asked what a COA was in my first week. Somebody linked the explainer and I have been reading them ever since.
comment on [Lab] 10th independent test on GL Biochem — 99.4% on a claimed 99.0%, and the trend is the interesting part in c/researchpeptides · 37 points · 1 year ago
Ordered under a name that turned out to cover two different molecules. Nobody’s fault but mine for not asking.
comment on unpopular opinion: most of what gets said here about pharmacology is guesswork in c/glp1science · 38 points · 1 year ago
read the discussion section, that is where the honesty lives
Agreed — and it is why the central and peripheral stories are complementary rather than rival.
comment on what changed for me between month 11 and month 16 in c/newbiequestions · 1 points · 1 year ago
the injection is easier than you are imagining
comment on why does nobody talk about appetite in c/glp1science · 52 points · 1 year ago
Asked a question here that I thought was stupid and got three papers back. Best thread I have been in on this site.