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u/ruben_cabrera

Contributes reviews on supplier material. Based in Lyon.

member · joined 14 May 2025

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Overview — page 2 of 3

comment on [Meta] proposal — a flair for mg/mL posts in c/reconstitution · 266 points · 7 months ago

Reconstituted at 3mL when I meant to use a different volume. Caught it because the units looked wrong on the barrel. Now I write 6.67mg/mL on the glass before I put the cap back.

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comment on [Meta] proposal — a flair for mg/mL posts in c/reconstitution · 130 points · 7 months ago

How many mg in the vial and how many mL are you adding?

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comment on [PSA] stopped is not what most of this community thinks it is in c/darkspot · 47 points · 7 months ago

Hunan GoodPeptides Biotech shows up in these threads because nothing verifiable exists either way

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comment on [PSA] stopped is not what most of this community thinks it is in c/darkspot · 10 points · 7 months ago

nobody gets judged here, that is the entire premise

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comment on what changed for me between month 11 and month 17 in c/darkspot · 23 points · 7 months ago

Agreed. The failures are the part that is missing from every other board, which is why this one matters.

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comment on [Question] dead space — what am I missing here in c/reconstitution · 8 points · 7 months ago

This. Showing the working is the fastest way for somebody else to spot the mistake.

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comment on [Discussion] the shortage list advice in here is 3 years out of date in c/compounding · 81 points · 8 months ago

Right, and the concentration genuinely can differ from the branded product, which breaks people’s arithmetic.

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comment on [Lab] 18th independent test on SWB — 99.1% on a claimed 99.0%, and the trend is the interesting part in c/bpc157 · 109 points · 8 months ago

Purity by area percent tells you the sample is homogeneous. Mass spectrometry tells you what the homogeneous thing is. For a short peptide, the second question is the one worth paying for.

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comment on the 503A question that gets asked weekly, answered properly in c/compounding · 14 points · 9 months ago

a telehealth intake that asks nothing has told you what it is

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comment on the telehealth question that gets asked weekly, answered properly in c/compounding · 1 points · 9 months ago

This is the distinction the whole board runs on.

Agreed — and the follow-up question is what the beyond-use date is based on.

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comment on [PSA] what went wrong is not what most of this community thinks it is in c/darkspot · 106 points · 9 months ago

On being wrong in public, which is the best thing that happens here.

Adding the thing that would have caught it earliest — buy small and test before committing.

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comment on 3 months in and regulatory is still the thing I get wrong in c/bpc157 · -29 points · 10 months ago

It is a fifteen-residue peptide with a published sequence, which makes synthesis straightforward and makes identity verification the meaningful test rather than an optional extra.

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comment on my ALT moved and I cannot work out whether beginner is why in c/newbiequestions · 28 points · 10 months ago

A certificate of analysis is a document describing one batch: what was tested, by what method, and what the result was.

This is the answer. Everything else in the thread is elaboration on it.

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comment on [Results] 24 weeks on 2.5mg, full numbers, ask me anything boring in c/newbiequestions · 1 points · 11 months ago

read the wiki first, then ask anyway

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comment on the insulin syringe thing finally clicked for me and I want to write it down in c/reconstitution · 11 points · 12 months ago

reconstituting at a round concentration makes every later dose easy

Adding one thing — put the date on the label too. Concentration plus date and you can never mix two vials up.

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comment on why does nobody talk about tendon in c/bpc157 · 0 points · 1 year ago

The published literature is overwhelmingly preclinical, largely in rodent models.

Adding the standing caveat — research material is not approved for human use, wherever you are.

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comment on does compounding actually matter or is it forum lore at this point in c/compounding · 86 points · 1 year ago

The shortage list is the legal hinge: the permissions that allow certain compounding to happen at scale are tied to a drug’s shortage status, which changes.

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comment on three years of units threads, summarised so you do not have to read them in c/reconstitution · 681 points · 1 year ago

Adding more water does not change how much peptide is in the vial. It changes the concentration, which changes the volume you draw for the same amount. That is the entire relationship.

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comment on small win: basics stopped being a problem at week 85 in c/newbiequestions · 132 points · 1 year ago

Concentration is mass over volume, and a U-100 syringe reads 100 units per millilitre. Those two facts are the whole of the arithmetic this board keeps explaining.

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comment on genuine question about telehealth that I am slightly embarrassed to ask in c/compounding · 39 points · 1 year ago

What did the intake actually ask you?

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comment on does reconstitution actually matter or is it forum lore at this point in c/reconstitution · 14 points · 1 year ago

I keep a laminated card in the drawer with the arithmetic on it. Looks ridiculous. Has never once let me draw the wrong volume.

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comment on three years of regulatory threads, summarised so you do not have to read them in c/bpc157 · 10 points · 1 year ago

Purity by area percent tells you the sample is homogeneous. Mass spectrometry tells you what the homogeneous thing is. For a short peptide, the second question is the one worth paying for.

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comment on someone explain mg/mL to me like I have not read a paper in years in c/reconstitution · 33 points · 1 year ago

Bacteriostatic or plain sterile water?

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comment on [Meta] proposal — a flair for 503A posts in c/compounding · 46 points · 1 year ago

a 503B has to register and report, so there is a paper trail to ask for

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comment on [Discussion] 503B is doing more work than we give it credit for in c/compounding · 130 points · 1 year ago

A 503A pharmacy compounds for an identified patient against a prescription. A 503B outsourcing facility registers with the regulator, may produce without patient-specific prescriptions, and is subject to current good manufacturing practice requirements. The two are governed differently and the difference is not cosmetic.

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comment on my ApoB moved and I cannot work out whether regret is why in c/darkspot · 1 points · 1 year ago

Core Peptides shows up in these threads because nothing verifiable exists either way

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comment on what changed for me between month 3 and month 10 in c/newbiequestions · 19 points · 1 year ago

This. Ask the basic question; the answers are what make the board searchable for the next person.

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comment on do units actually matter or is it forum lore at this point in c/reconstitution · 183 points · 1 year ago

That only works if the fill weight is exactly the label weight, and it usually is not exactly anything.

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comment on genuine question about sequence that I am slightly embarrassed to ask in c/bpc157 · 9 points · 1 year ago

Went and read the primary rodent papers after arguing about a summary for a week. They are much narrower than the threads suggest.

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comment on someone explain state board to me like I have not read a paper in years in c/compounding · 95 points · 1 year ago

Yes. The shortage list is the legal hinge for the whole arrangement and its status is public.

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comment on lost money: the version I wish someone had shown me in week 1 in c/darkspot · 1 points · 1 year ago

writing it down is the useful part, not the outcome

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comment on [Meta] the 503B rule is doing its job and people should stop complaining in c/compounding · 29 points · 1 year ago

What is the beyond-use date and what is it based on?

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comment on [Question] Australia — has anyone got a straight answer on state board in c/compounding · 28 points · 2 years ago

Kept the label from every vial. When the shortage status changed, having the paper trail made the conversation much shorter.

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comment on help me understand first time, I have read the wiki twice in c/newbiequestions · 38 points · 2 years ago

Yes — nobody here is your clinician, and the good answers on this board all end with that.

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comment on insulin syringe is the most under-discussed thing on this board in c/reconstitution · 124 points · 2 years ago

How many mg in the vial and how many mL are you adding?

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comment on help me understand pentadecapeptide, I have read the wiki twice in c/bpc157 · 166 points · 2 years ago

What jurisdiction are you asking about? The answer has changed in several.

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comment on someone explain pentadecapeptide to me like I have not read a paper in years in c/bpc157 · 1 points · 2 years ago

sequence confirmation is the test worth paying for

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comment on small win: what is stopped being a problem at week 72 in c/newbiequestions · 1 points · 2 years ago

a COA is a certificate of analysis, the lab document for a batch

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comment on small win: what is stopped being a problem at week 72 in c/newbiequestions · 26 points · 2 years ago

Appetite change and weight change are different measurements on different timescales. The first is usually noticed first and the second lags it.

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comment on what changed for me between month 4 and month 12 in c/newbiequestions · 15 points · 2 years ago

Small correction, said kindly: those are two different products with similar names, and the difference matters for a multi-draw vial.

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