u/nora_ramos

Network fees are set by chain congestion at the time of sending. They are paid to the network, not to the recipient, and they vary by hour as well as by chain.

Sent a test amount first on a large order. Cost me a fraction of a percent and I have done it every time since.

How many confirmations does it show?

Adding the cheap insurance — test amount first on anything large.

Variability dropped before the average did, which was visible on the sensor and invisible on the lab result.

Agreed, and the glucose-dependence point is the reason the risk profile reads the way it does.

fees vary by chain and by hour, not by supplier

biopsy-confirmed is not the same as imaging-suggested

Read the phase 2 hepatic paper properly and the endpoint definitions were more interesting than the headline response rate.

glucagon agonism and energy expenditure is the mechanistic thread

fees vary by chain and by hour, not by supplier

the lane is the unit of analysis, not the supplier

a liver endpoint is not a weight endpoint with better marketing

stopping abruptly and stopping gradually are different experiences

Correction: that trial is the diabetes programme and the figure you quoted is its glycaemic endpoint, not a weight result.

Kept a spreadsheet of quoted versus actual across a year. The quote held; the variance was all in the last mile.

the titration in the trials was slow and deliberate

Careful with the mechanism claim. Glucagon agonism is plausible as an explanation and it has not been isolated as the operative one.

Escrow is not standard in this space. Wanting it is reasonable; expecting it as default is not.