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u/lipid_panel_larry

Full panel every 12 weeks since 2023. ApoB is the number I actually watch.

long-standing contributor · bloodwork · joined 14 Nov 2023

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131comments

Comments — page 3 of 3

comment on A1c — 9 things I got wrong before I got it right in c/bloodwork · 9 points · 1 year ago

same lab, same conditions, or you are comparing noise

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comment on A1c — 9 things I got wrong before I got it right in c/bloodwork · 30 points · 1 year ago

Left up. It is a question about how to compare panels, not a request for interpretation.

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comment on anyone else notice lipids kicking in around week 9 in c/bloodwork · 61 points · 1 year ago

Time of day, fasting state, hydration and recent exercise all move common markers. Standardising the draw conditions is free and it removes most of the apparent variability.

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comment on stalled for 6 weeks at 1.7mg and I refuse to panic this time in c/bloodwork · 20 points · 1 year ago

How many weeks between the two measurements?

This is the sentence to read before anybody panics about a single value.

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comment on how much of what we believe about API source actually comes from telehealth threads in c/compounding · 453 points · 1 year ago

This. Compounded preparations carry no equivalence claim, and treating them as generics is a category error people make constantly.

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comment on USDC is the most under-discussed thing on this board in c/cryptopay · 5 points · 1 year ago

What is and is not the supplier’s fault, since this board generates unfair complaints.

Not theirs: the network fee, chain congestion, confirmation time, the rate moving between quote and send, and a payment sent on the wrong chain. Theirs: which networks they accept, how quickly they credit a confirmed payment, and whether the address they gave you was correct and communicated clearly.

Keeping those columns separate makes the reports here far more useful. A thread titled "supplier took my payment" that turns out to describe forty minutes of unconfirmed transaction helps nobody and follows people around for years.

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comment on [Discussion] special authorization is doing more work than we give it credit for in c/glp1canada · 26 points · 1 year ago

Kept every form and reference number. When they had no record of a submission, I did.

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comment on the compounding thing finally clicked for me and I want to write it down in c/compounding · 13 points · 1 year ago

That figure is the starting material purity, not the finished preparation potency. Two different tests.

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comment on CagriSema: the version I wish someone had shown me in week 1 in c/cagrilintide · 56 points · 1 year ago

The engineering problem was duration: native amylin is short-acting and aggregation-prone. A long-acting analogue suitable for weekly administration is what makes the combination clinically interesting.

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comment on ferritin — 15 things I got wrong before I got it right in c/bloodwork · 388 points · 1 year ago

nothing on this board interprets your results for you

Adding the obvious one — take it to whoever ordered the panel. This board cannot read it for you.

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comment on ferritin — 15 things I got wrong before I got it right in c/bloodwork · 128 points · 1 year ago

Have you taken this to whoever ordered it?

bac_water_bandit is right that a reference interval is not a target. It is a description of a population.

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comment on [Discussion] 503B is doing more work than we give it credit for in c/compounding · 191 points · 1 year ago

a telehealth intake that asks nothing has told you what it is

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comment on [Discussion] can we stop arguing about lipids until somebody posts a number in c/bloodwork · 37 points · 1 year ago

one measurement is a point, two is a line, three is a trend

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comment on [Discussion] can we stop arguing about lipids until somebody posts a number in c/bloodwork · 114 points · 1 year ago

How to make a panel worth comparing, which is most of the value people leave on the table.

Standardise the conditions: same lab, same fasting state, same rough time of day, same point in the week, similar hydration. Take a baseline before you change anything. Repeat any surprising value before acting on it. Change one thing at a time if you want to attribute anything to it.

Do that and a year of panels is a trend. Skip it and a year of panels is a collection of unrelated mornings, which is what most of the alarmed posts here are actually describing.

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comment on [Discussion] can we stop arguing about lipids until somebody posts a number in c/bloodwork · 438 points · 1 year ago

Left up. It is a question about how to compare panels, not a request for interpretation.

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comment on unpopular opinion: most of what gets said here about USDC is guesswork in c/cryptopay · 129 points · 1 year ago

Small fix — that is the network fee, not a supplier charge. The distinction matters for the complaint you are making.

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comment on how much of what we believe about eGFR actually comes from A1c threads in c/bloodwork · 13 points · 1 year ago

Small fix — a reference interval is not a treatment target, and the post above uses them interchangeably.

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comment on how much of what we believe about eGFR actually comes from A1c threads in c/bloodwork · 232 points · 1 year ago

Correction: that marker is reported in different units by different labs, which explains the tenfold difference you are seeing.

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comment on how much of what we believe about eGFR actually comes from A1c threads in c/bloodwork · 123 points · 1 year ago

Compared two draws across two labs and spent a week worrying before finding out the assays were different.

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comment on reading lipids threads from 2024 and half of it aged badly in c/bloodwork · 1 points · 1 year ago

draw at the same point in the week if you want comparability

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comment on [Results] 38 weeks, 6kg, and satiety was the hard part in c/cagrilintide · 3 points · 1 year ago

Complementary mechanisms are the rationale for pairing: satiety signalling alongside incretin signalling, rather than more agonism at the same receptor.

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comment on reading lipids threads from 2024 and half of it aged badly in c/bloodwork · 30 points · 1 year ago

The confounding problem, stated plainly, because this board keeps stepping on it.

Substantial weight loss moves lipids, liver enzymes, insulin sensitivity markers and several others in its own right. If you are losing weight while taking something, any change in those markers has at least two candidate explanations and you cannot separate them from your own panel.

What you can do is standardise, take a baseline, keep the series long, and be honest in your posts about what is and is not attributable. The threads that say "this compound did X to my triglycerides" almost never have the design to support the claim, mine included.

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comment on reading private plan threads from 2024 and half of it aged badly in c/glp1canada · 5 points · 1 year ago

Confused a rejected claim with a denied authorization for a month and pursued entirely the wrong process.

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comment on [Meta] the confirmations rule is doing its job and people should stop complaining in c/cryptopay · 245 points · 1 year ago

Confirmations are the count of blocks built on top of the one containing your transaction. Until there are some, the transaction is not settled in any meaningful sense.

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comment on how much of what we believe about ferritin actually comes from bloodwork threads in c/bloodwork · 1 points · 1 year ago

same lab, same conditions, or you are comparing noise

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comment on how much of what we believe about ferritin actually comes from bloodwork threads in c/bloodwork · 262 points · 1 year ago

Retitled — the original asserted a causal claim the post does not support.

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comment on [Meta] the Australia rule is doing its job and people should stop complaining in c/glp1aus · 3 points · 1 year ago

Careful, personal importation provisions are narrow and specific and the general version circulating here is wrong.

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comment on my fasting insulin moved and I cannot work out whether contraception is why in c/glp1women · 40 points · 1 year ago

That trial did not enrol the population you are asking about, so it cannot answer this.

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comment on the crypto thing finally clicked for me and I want to write it down in c/cryptopay · -32 points · 1 year ago

Network fees are set by chain congestion at the time of sending. They are paid to the network, not to the recipient, and they vary by hour as well as by chain.

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comment on [Discussion] can we stop arguing about baseline labs until somebody posts a number in c/bloodwork · 59 points · 1 year ago

How to make a panel worth comparing, which is most of the value people leave on the table.

Standardise the conditions: same lab, same fasting state, same rough time of day, same point in the week, similar hydration. Take a baseline before you change anything. Repeat any surprising value before acting on it. Change one thing at a time if you want to attribute anything to it.

Do that and a year of panels is a trend. Skip it and a year of panels is a collection of unrelated mornings, which is what most of the alarmed posts here are actually describing.

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comment on [Discussion] the PBS advice in here is 3 years out of date in c/glp1aus · 5 points · 1 year ago

What did the pharmacy quote for the private price?

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comment on [Discussion] the chargeback advice in here is 3 years out of date in c/cryptopay · -21 points · 1 year ago

Memo requirements are chain-specific. The chain you are describing does not use one.

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comment on the ApoB thing finally clicked for me and I want to write it down in c/bloodwork · 279 points · 1 year ago

baseline before you start is worth more than any later panel

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comment on the ApoB thing finally clicked for me and I want to write it down in c/bloodwork · 117 points · 1 year ago

ApoB counts atherogenic particles rather than the cholesterol they carry, which is why it can diverge from LDL-C and why it is the addition most worth making.

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comment on [Question] special authorization — what am I missing here in c/glp1canada · 12 points · 1 year ago

Not convinced. A rejected claim at the counter is not a denied authorization and the next step differs.

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comment on [Question] special authorization — what am I missing here in c/glp1canada · 0 points · 1 year ago

Correction: that is regulatory approval, not coverage. They are separate decisions by separate bodies.

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comment on [Discussion] we are measuring contraception at the wrong time and calling it noise in c/glp1women · 169 points · 1 year ago

Disagree — that is a general claim about absorption and the specific question needs a pharmacist rather than a board.

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comment on reading ALT threads from 2024 and half of it aged badly in c/bloodwork · 96 points · 1 year ago

Left up. It is a question about how to compare panels, not a request for interpretation.

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comment on the TGA question that gets asked weekly, answered properly in c/glp1aus · 69 points · 1 year ago

Disagree — that is registration status, and the question was about subsidy. Different decisions, different bodies.

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comment on insulin resistance — my 21-week log, condensed into one table in c/glp1women · 11 points · 1 year ago

the trials were not designed to answer most of the questions asked here

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