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KA

u/kaia_wojcik

Contributes reviews on supplier material. Based in Bochum.

member · joined 12 Mar 2025

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Overview — page 2 of 2

comment on is it normal to get muscle cramps at week 88 in c/survodutide · 0 points · 1 year ago

Which endpoint — histological response, fibrosis improvement, or fat fraction?

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comment on is it normal to get muscle cramps at week 88 in c/survodutide · 1 points · 1 year ago

Small fix — dual agonist, GLP-1 and glucagon. No GIP arm in this molecule.

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comment on is it normal to get muscle cramps at week 88 in c/survodutide · 129 points · 1 year ago

Correcting myself: the readout I quoted was the 4-week interim rather than the endpoint.

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comment on how much of what we believe about dual agonist actually comes from GIP threads in c/tirzepatide · 279 points · 1 year ago

23kg over 69 weeks, never went past 10mg, and constipation stayed mild the whole way. Posting because the loud threads are all 15mg.

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comment on how much of what we believe about dual agonist actually comes from GIP threads in c/tirzepatide · 96 points · 1 year ago

Not sure that follows.

Saving this one. It is the clearest statement of the stall problem I have read here.

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comment on how much of what we believe about dual agonist actually comes from GIP threads in c/tirzepatide · 404 points · 1 year ago

week 5 is early to draw any conclusion at all

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comment on [Results] 12 weeks on 1.7mg, full numbers, ask me anything boring in c/progresspics · -28 points · 1 year ago

Body weight varies by a couple of kilos day to day through fluid, glycogen and gut content, which is why a single weigh-in is noise and a fortnightly trend is signal.

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comment on help me understand 15mg, I have read the wiki twice in c/tirzepatide · 0 points · 1 year ago

sulphur burps are the signature complaint and they are not dangerous

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comment on [Question] how do you actually verify timeframe in c/progresspics · 38 points · 1 year ago

Agreed — text only was the best rule this board ever adopted. The posts are about what actually changed rather than about lighting.

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comment on [Question] how do you actually verify timeframe in c/progresspics · 55 points · 1 year ago

That is a waist measurement, not a weight, and the thread has been comparing them as though they were the same.

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comment on why does nobody talk about survodutide in c/survodutide · 7 points · 1 year ago

dual GLP-1 and glucagon agonist, and the glucagon arm is the story

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comment on glucagon is the most under-discussed thing on this board in c/survodutide · 0 points · 1 year ago

This is the framing the board needs.

Disagreeing with this bit: that number comes from a different programme with a different population.

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comment on small win: dual agonist stopped being a problem at week 50 in c/tirzepatide · 22 points · 1 year ago

It is a dual GIP and GLP-1 receptor agonist, and the GIP arm is the part that has no equivalent in the semaglutide threads. That is why the side-effect profile reads differently rather than just milder.

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comment on small win: glucagon stopped being a problem at week 36 in c/survodutide · 186 points · 2 years ago

Went slowly because everything published describes a deliberate escalation. That is the extent of what I will say about it.

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comment on [Meta] the goal rule is doing its job and people should stop complaining in c/progresspics · 172 points · 2 years ago

Right — the non-scale victories are the ones I remember. The numbers all blur together after a while.

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comment on milestone — 11 things I got wrong before I got it right in c/progresspics · 18 points · 2 years ago

nobody owes anybody a starting weight

Agreed — measurements over photographs, every time, for anybody trying to actually track something.

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comment on [Lab] split one vial across Medutest and Janoshik — 98.3% and 98.7% in c/tirzepatide · 394 points · 2 years ago

SURMOUNT-1 ran 72 weeks with the top arm around 21% mean body weight change. SURPASS is the diabetes programme and reports glycaemic endpoints, so quoting the two interchangeably is a category error.

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comment on the Mounjaro thing finally clicked for me and I want to write it down in c/tirzepatide · 120 points · 2 years ago

Cosigning the four-week thing. It is a minimum interval, and treating it as a schedule to keep up with is how people end up miserable at 12.5.

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