u/intent_to_treat
ITT vs per-protocol explains half the arguments on this site.
member · joined 23 Feb 2024
Comments — page 2 of 2
comment on [Question] data logger — what am I missing here in c/coldchain · 173 points · 1 year ago
You cannot infer potency from a temperature record. The record tells you what happened to the box; only a test tells you what happened to the material.
comment on small win: dose history stopped being a problem at week 6 in c/dosinglogs · 70 points · 1 year ago
What are you actually recording each week?
comment on what changed for me between month 11 and month 16 in c/newbiequestions · 53 points · 1 year ago
Research-use-only material is not approved for human use. That is a plain statement of regulatory fact and it belongs in every beginner thread.
comment on baseline labs: the version I wish someone had shown me in week 1 in c/bloodwork · 165 points · 1 year ago
Time of day, fasting state, hydration and recent exercise all move common markers. Standardising the draw conditions is free and it removes most of the apparent variability.
comment on ferritin — 15 things I got wrong before I got it right in c/bloodwork · 433 points · 1 year ago
Nobody here can interpret your panel and this comment is not doing so. What a board can usefully do is help you ask better questions of somebody who can.
comment on [Discussion] can we stop arguing about lipids until somebody posts a number in c/bloodwork · 24 points · 1 year ago
lab reference ranges are not treatment targets
comment on how much of what we believe about eGFR actually comes from A1c threads in c/bloodwork · 71 points · 1 year ago
Same view — ApoB if you add one thing. It answers a question the standard panel only gestures at.
comment on [Vendor] BCH order #16 — Germany, 4 days, no drama, receipts inside in c/coldchain · 31 points · 1 year ago
Once in solution, the relevant risks are hydrolysis, aggregation and, for some sequences, oxidation. Refrigeration slows all three; freezing a solution introduces a separate risk at the ice interface.
comment on how much of what we believe about beginner actually comes from what is threads in c/newbiequestions · 453 points · 1 year ago
What is the actual question underneath the question? Happy to answer both.
comment on how much of what we believe about beginner actually comes from what is threads in c/newbiequestions · 152 points · 1 year ago
Wrote the concentration on the vial after reading it here. Have never once had to reconstruct it from memory since.
comment on how much of what we believe about beginner actually comes from what is threads in c/newbiequestions · 245 points · 1 year ago
search first, but a repeat question is not a crime
comment on [Discussion] can we stop arguing about eGFR until somebody posts a number in c/bloodwork · 23 points · 1 year ago
My hs-CRP moved and I spent a fortnight convinced I knew why. The repeat six weeks later was back in range and I had changed nothing.
comment on [Discussion] can we stop arguing about eGFR until somebody posts a number in c/bloodwork · 122 points · 1 year ago
Brought the whole set to my clinician rather than one flagged value. Completely different conversation.
comment on help me understand first time, I have read the wiki twice in c/newbiequestions · 160 points · 2 years ago
the first month is a tolerance check, not a results phase
comment on three years of normal threads, summarised so you do not have to read them in c/newbiequestions · 220 points · 2 years ago
no question is too basic here, that is the entire point of the board
comment on how much of what we believe about weekly update actually comes from tracking threads in c/dosinglogs · 5 points · 2 years ago
Small fix — that is a reconstructed entry rather than a contemporaneous one, and the post presents it as the latter.
comment on [Discussion] can we stop arguing about ApoB until somebody posts a number in c/bloodwork · 2 points · 2 years ago
a single ApoB outside range is a reason to repeat, not to panic
comment on [Discussion] can we stop arguing about ApoB until somebody posts a number in c/bloodwork · 59 points · 2 years ago
ask whether the lab changed its assay between your two draws
Disagreeing with this bit: that change is confounded by the weight loss itself and cannot be attributed.
comment on three years of what is threads, summarised so you do not have to read them in c/newbiequestions · 1 points · 2 years ago
Yes — nobody here is your clinician, and the good answers on this board all end with that.
comment on the basics question that gets asked weekly, answered properly in c/newbiequestions · 118 points · 2 years ago
Gently disagree with the framing — nothing has gone wrong. Week 2 looking flat is the ordinary experience.
comment on anyone else notice baseline labs kicking in around week 7 in c/bloodwork · 1 points · 2 years ago
weight loss itself moves several of these independently
comment on [Meta] the stability rule is doing its job and people should stop complaining in c/coldchain · 51 points · 2 years ago
Gel pack fully liquid on arrival, powder tested 99.6% against a claimed 99.0% afterwards. The pack had done its job for as long as it was designed to.