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u/honest_syringe_2025

Not a chemist. Increasingly acting like one.

newer member · joined 7 Apr 2025

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Comments — page 3 of 3

comment on [Results] 24 weeks on 12.5mg, full numbers, ask me anything boring in c/glp1women · 9 points · 1 year ago

Agreed — logging the cycle alongside everything else is what made my own pattern visible. It was invisible before that.

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comment on someone explain discontinuation to me like I have not read a paper in years in c/tapering · 1 points · 1 year ago

decide what you are watching for before you stop

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comment on does reconstitution actually matter or is it forum lore at this point in c/reconstitution · 22 points · 1 year ago

more water is not more drug, it is the same drug in a bigger volume

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comment on contraception — 16 things I got wrong before I got it right in c/glp1women · 1 points · 1 year ago

Started logging the cycle in the same sheet as the dose. Three months later the pattern was obvious and it had been invisible before.

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comment on [Question] is 99.2% actually fine or am I being sold a rounding error in c/hplc · 84 points · 1 year ago

baseline choice is a decision, not a measurement

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comment on how much of what we believe about API source actually comes from telehealth threads in c/compounding · 158 points · 1 year ago

503A or 503B — do you know which?

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comment on USDC is the most under-discussed thing on this board in c/cryptopay · -6 points · 1 year ago

network and address, checked twice, before anything else

Adding the cheap insurance — test amount first on anything large.

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comment on triple agonist: the version I wish someone had shown me in week 1 in c/retatrutide · 1 points · 1 year ago

What the glucagon arm is doing, as best anyone can say from public data.

discount_math_dm is right about the escalation being the variable. It explains most of the difficult reports here.

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comment on the bacteriostatic water question that gets asked weekly, answered properly in c/reconstitution · 27 points · 1 year ago

Research-use-only material is not approved for human use, so treat everything in this thread as arithmetic about solutions rather than instructions fo

Disagreeing with this line only: adding more water is not a safety margin, it is a different divisor.

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comment on the bacteriostatic water question that gets asked weekly, answered properly in c/reconstitution · 74 points · 1 year ago

Shook the first vial because nobody told me not to. It was fine, but I have swirled every one since.

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comment on [Vendor] FGP order #12 — Germany, 4 days, no drama, receipts inside in c/cryptopay · 1 points · 1 year ago

the memo field matters on the chains that use one

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comment on [Lab] WXT reta — PeptideMeter came back 97.7% against a claimed 97.0% in c/retatrutide · 48 points · 1 year ago

phase 2 data only, and people quote it like it is a label

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comment on someone explain mg/mL to me like I have not read a paper in years in c/reconstitution · 83 points · 1 year ago

Wrote the date on the vial as well as the concentration after losing track of which one was opened first.

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comment on someone explain mg/mL to me like I have not read a paper in years in c/reconstitution · 226 points · 1 year ago

I keep a laminated card in the drawer with the arithmetic on it. Looks ridiculous. Has never once let me draw the wrong volume.

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comment on [Meta] proposal — a flair for 503A posts in c/compounding · 175 points · 1 year ago

the pharmacy and the prescriber are two separate questions

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comment on [Meta] the concentration rule is doing its job and people should stop complaining in c/reconstitution · 357 points · 1 year ago

The dead space question sent me down a rabbit hole for a week. It is a fraction of a unit and it is the same every draw.

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comment on [Meta] the concentration rule is doing its job and people should stop complaining in c/reconstitution · 103 points · 1 year ago

That is sterile water, not bacteriostatic. Same appearance, different product, and it matters for a multi-draw vial.

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comment on [Meta] the concentration rule is doing its job and people should stop complaining in c/reconstitution · 59 points · 1 year ago

What concentration did you actually reconstitute at, rather than what did you intend to?

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comment on [Lab] CPC cagri — Janoshik came back 98.1% against a claimed 97.5% in c/hplc · 46 points · 1 year ago

integration decisions move the number more than the sample does

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comment on genuine question about phase 2 that I am slightly embarrassed to ask in c/retatrutide · 190 points · 1 year ago

That is body weight change, not fat mass. The trials report the first and people quote it as the second.

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comment on why does nobody talk about gradient in c/hplc · 83 points · 1 year ago

ghost peak, check the plumbing first, it is always the plumbing

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comment on [Question] how do you actually verify cycle in c/glp1women · 23 points · 1 year ago

The same dose genuinely feels different at different points in the month for me. Took a year to notice and it was in the log the whole time.

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comment on my fasting insulin moved and I cannot work out whether contraception is why in c/glp1women · 4 points · 1 year ago

Correction: that trial did not enrol the population being discussed, so it cannot support the claim.

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comment on 3 months in and triple agonist is still the thing I get wrong in c/retatrutide · 89 points · 1 year ago

Watched heart rate on a wearable across twelve weeks because the threads said to. It moved a little and I have no idea whether that means anything.

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comment on someone explain perimenopause to me like I have not read a paper in years in c/glp1women · 87 points · 1 year ago

Has this been raised with whoever prescribes?

Disagreeing with this line: the absorption question has a product-specific answer and a pharmacist has it.

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comment on TRIUMPH: what the trials say vs what this community says in c/retatrutide · 20 points · 1 year ago

Are you comparing against phase 3 numbers for something else? They are not comparable.

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comment on [Question] how do you actually verify gas fees in c/cryptopay · 4 points · 1 year ago

the same token exists on several chains and they are not interchangeable

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comment on method development — 10 things I got wrong before I got it right in c/hplc · 34 points · 1 year ago

Yes. Retention time is a hypothesis about identity. Mass is the answer.

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comment on reading chromatogram threads from 2024 and half of it aged badly in c/hplc · 32 points · 1 year ago

baseline choice is a decision, not a measurement

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comment on help me understand telehealth, I have read the wiki twice in c/compounding · 1 points · 1 year ago

the pharmacy and the prescriber are two separate questions

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comment on [Discussion] the insulin syringe advice in here is 2 years out of date in c/reconstitution · 0 points · 1 year ago

I keep a laminated card in the drawer with the arithmetic on it. Looks ridiculous. Has never once let me draw the wrong volume.

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comment on how much of what we believe about gradient actually comes from purity threads in c/hplc · 295 points · 1 year ago

you cannot report to two decimals off that baseline

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comment on how much of what we believe about gradient actually comes from purity threads in c/hplc · 66 points · 1 year ago

area percent is relative to what the detector saw and nothing else

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comment on [Meta] the cycle rule is doing its job and people should stop complaining in c/glp1women · 0 points · 2 years ago

Right, and symptom patterns tracking the cycle rather than the dose explains a lot of confusing weeks.

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comment on [Lab] split one vial across Janoshik and Medutest — 95.1% and 99.3% in c/retatrutide · 1 points · 2 years ago

comparing reta phase 2 to sema phase 3 is comparing different things

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comment on reading triple agonist threads from 2024 and half of it aged badly in c/retatrutide · 68 points · 2 years ago

phase 2 data only, and people quote it like it is a label

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comment on [Discussion] mg/mL is doing more work than we give it credit for in c/reconstitution · 19 points · 2 years ago

aim the stream at the glass wall, not at the cake

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comment on method development is the most under-discussed thing on this board in c/hplc · 374 points · 2 years ago

Chased a ghost peak for three weeks. It was the plumbing. It is always the plumbing.

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comment on what would you tell week-1 you about dose escalation in c/retatrutide · 55 points · 2 years ago

wait for phase 3 before you argue about rankings

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comment on unpopular opinion: most of what gets said here about crypto is guesswork in c/cryptopay · 1 points · 2 years ago

Nearly sent on the wrong network. The token symbol was identical and the address format was the only clue.

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