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HE

u/hedda_adeyemi

Contributes reviews on supplier material. Based in Oulu.

member · joined 14 May 2025

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Comments — page 3 of 3

comment on someone explain insulin syringe to me like I have not read a paper in years in c/reconstitution · 13 points · 1 year ago

Not quite. Bacteriostatic and sterile water are not interchangeable for a multi-draw vial, and the difference is the preservative.

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comment on [Meta] proposal — a flair for seizure posts in c/customs · 2 points · 1 year ago

Got a request for information and treated it as a seizure for two days before actually reading it. It was neither dramatic nor difficult.

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comment on [Meta] proposal — a flair for shipping posts in c/intlshipping · 58 points · 1 year ago

Same lane, four orders, 16 to 6 days, all four within a couple of days of the quote. That consistency is the actual finding.

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comment on [Meta] proposal — a flair for shipping posts in c/intlshipping · 50 points · 1 year ago

Median transit is the useful statistic. The minimum is a story about one shipment and the mean is dragged around by a single hold.

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comment on three years of insulin syringe threads, summarised so you do not have to read them in c/reconstitution · 13 points · 1 year ago

Correction: that gives 90 units, not what you have written. 5mg into 3mL is 1.67mg/mL and the division follows from there.

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comment on the TGA question that gets asked weekly, answered properly in c/glp1aus · 173 points · 1 year ago

Australia and New Zealand have different regulators, different funding bodies and different arrangements. An answer for one is not evidence about the other.

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comment on [Discussion] the dead space advice in here is 2 years out of date in c/reconstitution · 1 points · 1 year ago

The arithmetic in full: concentration is mass over volume, so 20mg into 3mL gives 6.67mg/mL. A U-100 syringe is graduated at 100 units per millilitre, so 1mg is 1 divided by 6.67 millilitres, which is 15 units.

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comment on help me understand SURMOUNT, I have read the wiki twice in c/trialwatch · 176 points · 2 years ago

Argued for a week about a result and then read the limitations section, which conceded most of my opponent’s point.

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comment on [PSA] New Zealand is not what most of this community thinks it is in c/glp1aus · 15 points · 2 years ago

I would not treat one pharmacy’s quote as the national price. Variation between them is substantial.

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comment on gastric emptying — 12 things I got wrong before I got it right in c/glp1science · 12 points · 2 years ago

This. Albumin binding and modification are why the half-life is what it is, and it is a design decision rather than an accident.

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comment on three years of Australia threads, summarised so you do not have to read them in c/glp1aus · 7 points · 2 years ago

That is a pharmacy-level stock issue rather than a national supply issue. They feel identical and are not.

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comment on nobody warned me about reflux and I would have liked the warning in c/bloodwork · 247 points · 2 years ago

Different laboratories use different assay platforms with different calibration. Comparing across labs adds a systematic offset that is invisible on the report.

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comment on SELECT: what the trials say vs what this community says in c/trialwatch · 29 points · 2 years ago

SELECT was cardiovascular outcomes, not weight

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comment on stalled for 13 weeks at 2.4mg and I refuse to panic this time in c/bloodwork · 314 points · 2 years ago

Different laboratories use different assay platforms with different calibration. Comparing across labs adds a systematic offset that is invisible on the report.

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comment on the transit time thing finally clicked for me and I want to write it down in c/intlshipping · -21 points · 2 years ago

Same lane in a different season for comparison?

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comment on reading SURMOUNT threads from 2024 and half of it aged badly in c/trialwatch · 127 points · 2 years ago

Spent an evening with the appendix tables and found the subgroup detail that the entire thread had been speculating about.

Adding the check nobody runs — the registered protocol is public and takes two minutes to compare.

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comment on help me understand transit time, I have read the wiki twice in c/intlshipping · 9 points · 2 years ago

Not convinced by four data points. That is not a lane yet, it is an anecdote with a route attached.

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comment on DHL is the most under-discussed thing on this board in c/intlshipping · 20 points · 2 years ago

Not convinced by four data points. That is not a lane yet, it is an anecdote with a route attached.

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comment on unpopular opinion: most of what gets said here about concentration is guesswork in c/reconstitution · 0 points · 2 years ago

What is written on the vial right now?

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comment on genuine question about reconstitution that I am slightly embarrassed to ask in c/reconstitution · 4 points · 2 years ago

Cosigning the round-number approach. Reconstituting to something awkward is how you end up drawing 27.5 units at six in the morning.

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