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posted 5 months ago by u/anders_karlsen
why does nobody talk about SELECTwhy does nobody talk about SELECT. Searched first, found three threads that contradict each other, hence the post. Spent an evening with the appendix tables and found…
c/trialwatch — top, page 2
Positions 26–50 of 95.
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posted 4 months ago by u/rt_shift_reggie
how much of what we believe about endpoint actually comes from TRIUMPH threadshow much of what we believe about endpoint actually comes from TRIUMPH threads. I would rather ask a basic question now than get this wrong quietly for two months. A…
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posted 7 months ago by u/curious_panel_only
SURPASS — 12 things I got wrong before I got it rightSURPASS — 12 things I got wrong before I got it right — a position I have arrived at slowly and would like tested. Relative risk reduction without the baseline rate is…
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someone explain FLOW to me like I have not read a paper in years
someone explain FLOW to me like I have not read a paper in years — that is what I am asking, and I have already read the wiki twice. Started keeping the trial…
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Reference standards, analytical reagents and system-suitability material. If you are running your own method, start with a known.
Reference standards2.2k
posted 12 months ago by u/milan_villalobos
[Discussion] the endpoint advice in here is 3 years out of datethe endpoint advice in here is 3 years out of date. It is the sort of thing everyone half-believes and nobody writes down. 3 years. Those are measured, not estimated,…
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posted 1 year ago by u/yannick_salinas
help me understand SURMOUNT, I have read the wiki twiceThe title is the whole question — help me understand SURMOUNT, I have read the wiki twice — but here is why I am asking. Discontinuation rates are a tolerability…
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posted 3 months ago by u/yara_mensah
[Question] endpoint — what am I missing hereendpoint — what am I missing here. I would rather ask a basic question now than get this wrong quietly for two months. Spent an evening with the appendix tables and…
2k
posted 1 year ago by u/laila_almeida
[Question] how do you actually verify SURPASShow do you actually verify SURPASS. I would rather ask a basic question now than get this wrong quietly for two months. A confidence interval is the range of effects…
2k
posted 1 year ago by u/paper_trail_paula
[Discussion] TRIUMPH is doing more work than we give it credit forTRIUMPH is doing more work than we give it credit for. Making the case below, and I expect to lose some of it in the comments. Argued for a week about a result and then…
2k
posted 6 months ago by u/nordic_pricing
someone explain FLOW to me like I have not read a paper in yearssomeone explain FLOW to me like I have not read a paper in years. Searched first, found three threads that contradict each other, hence the post. The discontinuation…
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posted 7 months ago by u/first_hundred
the STEP question that gets asked weekly, answered properlythe STEP question that gets asked weekly, answered properly. Not a hot take, just something I have not seen said plainly here. Spent an evening with the appendix tables…
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posted 5 months ago by u/joaquin_stanescu
how much of what we believe about endpoint actually comes from SURMOUNT threadsAsking properly rather than in a comment on somebody else’s thread: how much of what we believe about endpoint actually comes from SURMOUNT threads. Compared myself to…
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posted 2 months ago by u/joaquin_trevino
does SELECT actually matter or is it forum lore at this pointThe title is the whole question — does SELECT actually matter or is it forum lore at this point — but here is why I am asking. Went looking for the registered protocol…
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posted 8 months ago by u/rt_shift_reggie
SURPASS — 6 things I got wrong before I got it rightSURPASS — 6 things I got wrong before I got it right. It is the sort of thing everyone half-believes and nobody writes down. Spent an evening with the appendix tables…
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posted 2 years ago by u/hsa_math
how much of what we believe about endpoint actually comes from SURMOUNT threadshow much of what we believe about endpoint actually comes from SURMOUNT threads. I am not trying to be the "source?" guy. I would just like a source. How to read one of…
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Send the vial, get the number. Third-party purity and identity testing, results published to you regardless of what they say.
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glbiochem.net1.5k
posted 1 year ago by u/sofia_wikstrom
how much of what we believe about endpoint actually comes from STEP threadshow much of what we believe about endpoint actually comes from STEP threads. I would rather ask a basic question now than get this wrong quietly for two months. Spent…
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posted 1 months ago by u/careful_gradient_again
[Meta] the FLOW rule is doing its job and people should stop complainingPutting this to the board: the FLOW rule is doing its job and people should stop complaining. Why comparing across trials almost never works, with the specific failure…
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posted 1 year ago by u/rulebook_rachael
SELECT: what the trials say vs what this community saysSELECT: what the trials say vs what this community says — a position I have arrived at slowly and would like tested. Why comparing across trials almost never works,…
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posted 1 year ago by u/line_demir
[Discussion] can we stop arguing about TRIUMPH until somebody posts a numberTrying to get a straight answer on this: can we stop arguing about TRIUMPH until somebody posts a number. Compared myself to a trial mean for about six months before…
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posted 6 months ago by u/foam_head_fred
SURPASS — 14 things I got wrong before I got it rightSURPASS — 14 things I got wrong before I got it right. Making the case below, and I expect to lose some of it in the comments. Quoted a figure here confidently, got…
1.1k
posted 3 months ago by u/camila_vasquez
SELECT: what the trials say vs what this community saysThe title is the argument: SELECT: what the trials say vs what this community says. Here is the rest of it. Intention-to-treat analyses everybody randomised regardless…
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posted 7 months ago by u/laila_almeida
how much of what we believe about endpoint actually comes from SELECT threadshow much of what we believe about endpoint actually comes from SELECT threads — that is what I am asking, and I have already read the wiki twice. On means, which this…
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posted 2 years ago by u/yusuf_ramos
SURPASS — 22 things I got wrong before I got it rightSURPASS — 22 things I got wrong before I got it right. Not a hot take, just something I have not seen said plainly here. Spent an evening with the appendix tables and…
989
posted 17 days ago by u/customs_seizure_sid
[Paper] ATTAIN-1 — an oral pill with no food restrictions is a bigger deal than the % suggestsSomething I keep coming back to: ATTAIN-1 — an oral pill with no food restrictions is a bigger deal than the % suggests. Quoted a figure here confidently, got asked…
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posted 26 days ago by u/paper_trail_paula
[Meta] proposal — a flair for FLOW postsproposal — a flair for FLOW posts. Nothing about this affects the ranking maths, before anyone asks. The registered protocol is public. Comparing the registered primary…