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c/tirzepatide·submitted 1 year ago by u/samir_falk

help me understand SURMOUNT, I have read the wiki twice

Discussionbranch of 6 comments

help me understand SURMOUNT, I have read the wiki twice. If this has been answered properly somewhere, link me and I will delete. Switching from semaglutide, since three people asked in this thread alone. There is no published dose equivalence between the two. The conversion tables that circulate are somebody’s…

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6 comments, started 1 year ago
u/titration_marshalmod · c/semaglutide270 points·1 year ago

Research-use-only material is not approved for human use. Anything in this thread about how a research vial "should" titrate is a discussion about chemistry, not a plan.

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u/aksel_kjaer211 points·1 year ago

The 21% figure is a 72-week mean on the highest arm. Quoting it as what someone should expect by week 83 is not a fair reading.

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u/samir_falkOP112 points·1 year ago

Which week did the appetite change actually land for you?

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[removed]77 points·1 year ago

[removed by moderator]

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u/crosspost_bot_no63 points·1 year ago

Careful with "everyone tolerates it better". The people it did not suit stop posting, which makes this board look calmer than the drug is.

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u/kaia_cabrera64 points·1 year ago

Sulphur burps for the first eight days after each step, then nothing. Predictable enough that I planned my week around it.

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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