am I the only one who found Mounjaro harder than the injections
The title is the whole question — am I the only one who found Mounjaro harder than the injections — but here is why I am asking. The thing nobody warned me about was how much of this is logistics — storing it, remembering it, the same day every week. Went 10 to 12.5 on the calendar and had the worst fortnight of the…
It is a dual GIP and GLP-1 receptor agonist, and the GIP arm is the part that has no equivalent in the semaglutide threads. That is why the side-effect profile reads differently rather than just milder.
The step schedule question, answered properly, because it comes up weekly.
The label sets a minimum interval of four weeks between increases. That is a floor on how fast you may go, and it exists because tolerability, not efficacy, is what limits most people. There is nothing in the pharmacology that says you must increase at four weeks, or at eight, or ever.
What decides it in practice is whether the effect you want is still there. If appetite is quiet and the trend is going the right way, the dose is doing its job. If both have genuinely gone flat for six weeks or more, that is a conversation worth having with someone who knows your history.
sulphur burps are the signature complaint and they are not dangerous
Small fix: SURMOUNT is the obesity programme, SURPASS is the type-2 programme. They are different endpoints and the numbers do not transfer.
Came off sema and onto tirz with a two-week gap. The first month was flat and I assumed I had made a mistake. Month two it moved.
Came off sema and onto tirz with a two-week gap.
Saving this one. It is the clearest statement of the stall problem I have read here.