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c/tirzepatide·submitted 4 months ago by u/ingrid_correia

Mounjaro: the version I wish someone had shown me in week 1

Titrationbranch of 7 comments

Mounjaro: the version I wish someone had shown me in week 1, logged the same way every week so the comparison is at least internally fair. The step schedule question, answered properly, because it comes up weekly. The label sets a minimum interval of four weeks between increases. That is a floor on how fast you may…

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7 comments, started 4 months ago
u/customs_seizure_sid-18 points·4 months ago

Switching from semaglutide, since three people asked in this thread alone.

There is no published dose equivalence between the two. The conversion tables that circulate are somebody’s arithmetic, not data. What people report here is that the first month after a switch is often flat, that the appetite effect feels differently shaped rather than simply stronger, and that starting at the bottom of the ladder again is the common approach.

None of that is a recommendation. It is what the threads say, and the threads are not a clinic.

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u/quiet_moderatorMOD1 point·4 months ago

Left up, flair changed to Discussion. It is an opinion post and that is fine as long as it is labelled.

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u/gustav_vermeulen1 point·4 months ago

Left up, flair changed to Discussion.

Agreed, with one qualifier: that is the mean of the top arm and the spread around it was enormous.

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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