[Discussion] "tirz is stronger than sema" needs a comparator dose or it means nothing
"tirz is stronger than sema" needs a comparator dose or it means nothing. Making the case below, and I expect to lose some of it in the comments. Came off sema and onto tirz with a two-week gap. The first month was flat and I assumed I had made a mistake. Month two it moved. Held 7.5 for five months. Everyone kept…
Research-use-only material is not approved for human use. Anything in this thread about how a research vial "should" titrate is a discussion about chemistry, not a plan.
Research-use-only material is not approved for human use.
This. The step interval is a floor, and reading it as a timetable is the most expensive mistake in the thread.
dual agonist, so the GIP arm is doing something the sema threads will not tell you about
switching from sema is not a dose conversion, there is no clean equivalence
What step are you on and how long have you been there?
if 7.5 is working, 10 is not automatically better
Push back: "gentler than sema" is a population statement. Plenty of people on this board have the opposite experience and they are not doing it wrong.