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c/t2dglp1·submitted 2 years ago by u/santiago_rasmussen

5 months in and metformin is still the thing I get wrong

Cautionbranch of 6 comments

5 months in and metformin is still the thing I get wrong. This is a description of what happened to me and not a plan for anybody else. Numbers, in the order they matter: 5 months. The three numbers, and what each one can and cannot tell you. A1c is an average over about three months, weighted to the recent weeks. It…

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6 comments, started 2 years ago
u/emil_okwuosa11 points·2 years ago

Postprandial excursions flattened out first and the fasting number took months to follow. Nobody had told me to expect that order.

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u/stubborn_batchlist_maybe5 points·2 years ago

Yes — time in range tells you about variability, which the average deliberately hides.

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u/piotr_bruun1 point·2 years ago

Time in range told me far more than the average did. Two quarters with the same A1c looked completely different on the sensor.

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u/santiago_rasmussen2 points·2 years ago

a1c can be affected by things that have nothing to do with glucose

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u/iman_castellanos2 points·2 years ago

the diabetes trials report different endpoints from the obesity ones

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u/rania_marchand4 points·2 years ago

glycaemic control and weight are two different endpoints

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Type 2 diabetes as the original indication: A1c trajectories, CGM traces, hypoglycaemia risk when stacked with sulfonylureas or insulin, metformin combinations, and why the weight-loss conversation sometimes drowns out the glycaemic one.

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