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c/survodutide·submitted 2 months ago by u/lyophile_lou

[Results] 28 weeks, 11kg, and MASH was the hard part

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28 weeks, 11kg, and MASH was the hard part. Same spreadsheet I have been keeping since the start, nothing retrofitted. Since the title puts numbers in the shop window: 28 weeks and 11kg. Asked here what the difference was between the imaging and biopsy endpoints and got a genuinely excellent answer. Looked for…

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6 comments, started 2 months ago
u/nora_ramos-32 points·2 months ago

Nothing containing this compound is approved anywhere. Research-use-only material is not approved for human use.

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[removed]1 point·2 months ago

[removed by moderator]

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u/mod_cold_roommod · c/coldchain1 point·2 months ago

phase 2 in liver disease is a different evidence question from weight

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u/customs_seizure_sid1 point·2 months ago

fibrosis improvement without worsening steatohepatitis is the phrase to learn

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u/kaia_wojcik1 point·2 months ago

Agreed that the endpoint definitions matter enormously and almost nobody reads them before quoting a response rate.

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u/cato_batista1 point·2 months ago

dual GLP-1 and glucagon agonist, and the glucagon arm is the story

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