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c/retatrutide·submitted 7 months ago by u/fabio_lehtinen

help me understand glucagon, I have read the wiki twice

Labbranch of 7 comments

help me understand glucagon, I have read the wiki twice. Searched first, found three threads that contradict each other, hence the post. Went up slowly, deliberately, because everything on this board says the escalation is where trouble lives. Uneventful so far and I am not going to pretend that is a finding. Phase 2…

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7 comments, started 7 months ago
u/honest_syringe_2025455 points·7 months ago

small trial, big effect, wide error bars

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u/naomi_erdogan355 points·7 months ago

That is body weight change, not fat mass. The trials report the first and people quote it as the second.

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[removed]238 points·7 months ago

[removed by moderator]

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u/lina_bruun77 points·7 months ago

heart rate is the thing people report watching

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u/zeynep_mbeki151 points·7 months ago

Small fix — three receptors, not two. GLP-1, GIP and glucagon, and the third one is the reason this compound gets its own board.

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u/liver_enzyme_liz89 points·7 months ago

Has anyone posted an independent test on this compound recently?

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u/farid_molnar81 points·7 months ago

Kept a log specifically because there is so little published. It is one person and it is not data.

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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