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c/retatrutide·submitted 1 year ago by u/marta_vanhecke

[Results] 4 weeks on 15mg, full numbers, ask me anything boring

Resultsbranch of 8 comments

Here it is: 4 weeks on 15mg, full numbers, ask me anything boring. One person, one log, no control group, so read it accordingly. 4 weeks and 15mg — those are the numbers, and they are the ones I am willing to defend. What the glucagon arm is doing, as best anyone can say from public data. GLP-1 and GIP agonism cover…

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8 comments, started 1 year ago
u/honest_syringe_2025702 points·1 year ago

Agreed, and the framing that helps is: this is a phase 2 compound with phase 3 running. Everything else is inference.

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u/ismael_eriksen274 points·1 year ago

nothing here is available as a prescription product, so read every thread with that in mind

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u/marta_vanheckeOP140 points·1 year ago

Sent a vial to Medutest out of curiosity. Result was 99.6% against a claimed 99.0%, which is the first independent number I had seen for this compound anywhere.

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u/lane_watchermod · logistics64 points·1 year ago

a lot of the confident posting here is extrapolation

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u/dead_space_doug41 points·1 year ago

not approved anywhere, which is the single most important fact in this board

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u/rekha_vestergaard-20 points·1 year ago

Phase 2 estimates effect and finds a dose range. Phase 3 estimates it precisely in a bigger population and catches what phase 2 was too small to see. Treating them as the same tier of evidence is the recurring error here.

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u/hassan_nilsen464 points·1 year ago

Correction: TRIUMPH is the phase 3 programme. The number you are quoting is from the phase 2 readout, which is a different trial.

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u/cagrilintide_enthusiast228 points·1 year ago

Correction: TRIUMPH is the phase 3 programme.

Adding the standing caveat: none of this is approved anywhere and research material is not for human use.

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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