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c/retatrutide·submitted 2 years ago by u/lurker_for_years

stalled for 7 weeks at 10mg and I refuse to panic this time

Trial Databranch of 6 comments

Thinking out loud about this: stalled for 7 weeks at 10mg and I refuse to panic this time. 7 weeks and 10mg — those are the numbers, and they are the ones I am willing to defend. Independent purity testing on this compound is thin compared with the older molecules, simply because fewer members have paid for it. Fewer…

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6 comments, started 2 years ago
u/farid_molnar39 points·2 years ago

triple agonist — GLP-1, GIP and glucagon, and the glucagon arm is the new part

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u/tired_ledger_notes27 points·2 years ago

Agreed on the heart-rate reports. They are consistent enough across the threads to be worth noting, not enough to be a finding.

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u/baseline_drifteranalytical13 points·2 years ago·edited

How fast was the escalation? That is usually the variable that explains the reports.

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u/lurker_for_yearsOP16 points·2 years ago

What do you think the glucagon component is adding, specifically?

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u/nadia_norgaard8 points·2 years ago

research-use-only material is not approved for human use, full stop

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u/heart_rate_bump7 points·2 years ago

Small fix — three receptors, not two. GLP-1, GIP and glucagon, and the third one is the reason this compound gets its own board.

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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