unpopular opinion: most of what gets said here about TRIUMPH is guesswork
unpopular opinion: most of what gets said here about TRIUMPH is guesswork. Change my mind, genuinely — I have no stake in being right about this. The standing caveat, written out properly because it keeps getting compressed into a footnote. Nothing containing this compound is approved by any regulator.…
Read the phase 2 paper twice before ordering anything. Recommend that to anyone in this board: the error bars are the interesting part.
Increases in heart rate have been reported across this receptor class. The magnitude and clinical significance are exactly what phase 3 is powered to establish.
small trial, big effect, wide error bars
not approved anywhere, which is the single most important fact in this board
not approved anywhere, which is the single most important fact in this board
marta_vanhecke is right about the escalation being the variable. It explains most of the difficult reports here.
Sent a vial to VendorInvestigate out of curiosity. Result was 97.4% against a claimed 97.0%, which is the first independent number I had seen for this compound anywhere.
the phase 2 numbers were striking and they were also 48 weeks in a small population
a lot of the confident posting here is extrapolation